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单词 cytotoxin
释义

cytotoxinn.

Brit. /ˌsʌɪtə(ʊ)ˈtɒksɪn/, U.S. /ˌsaɪdəˈtɑks(ə)n/
Origin: Formed within English, by compounding; modelled on a French lexical item. Etymons: cyto- comb. form, toxin n.
Etymology: < cyto- comb. form + toxin n., after French cytotoxine (E. Metchnikoff 1900, in Ann. de l'Inst. Pasteur 14 369).
An antibody or other substance that has a toxic effect on cells; a cytotoxic agent.
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the world > life > biology > substance > process stimulators or inhibitors > toxin > [noun]
toxin1890
autointoxicant1891
autotoxin1894
leucocidin1894
cytotoxin1900
toxon1900
nephrotoxin1902
toxonoid1904
zootoxin1906
leucotoxin1908
phalloidin1909
vivotoxin1953
victorin1954
phalloin1959
bungarotoxin1963
pathotoxin1963
trichothecene1971
1900 Jrnl. Chem. Soc. 78 ii. 741 The term cytotoxin is introduced for those poisons of animal origin which act on the formed elements (cells, &c.) of organs.
1915 Practitioner Jan. 171 (title) Pituitary insufficiency and a pituitary antiserum or cytotoxin.
1964 M. Harris Cell Culture & Somatic Variation viii. 462 The possibility that cytotoxins and hemagglutins may be actually the same isoantibodies, demonstrated merely by two different techniques.
1988 Q. N. Myrvik & R. S. Weiser Fund. Med. Bacteriol. & Mycol. (ed. 2) x. 158 Both hemolysins are highly toxic for neutrophils and macrophages and streptolysin O is a general cytotoxin and cardiotoxin.
2003 Times (Nexis) 21 Mar. 2 Ricin is highly stable, making it easy to store and transport. It works as a cytotoxin, or cell poison, with a single molecule capable of killing a cell.
This entry has been updated (OED Third Edition, November 2010; most recently modified version published online March 2022).
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n.1900
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