acridinen.

Brit.

/ˈakrᵻdiːn/,

/ˈakrᵻdʌɪn/, U.S.

/ˈækrəˌdin/,

/ˈækrəd(ə)n/

Origin: Formed within English, by derivation; modelled on a German lexical item. Etymons: acrid adj., -idine suffix.

Etymology: < acr- (in acrid adj.) + -idine suffix, after German Acridin (C. Graebe and H. Caro 1870, in Berichte der Deutsch. Chem. Ges. 3 746).

Chemistry.

A crystalline heterocyclic compound which occurs naturally in coal tar, is an irritant of the skin and mucous membranes, and is used in the manufacture of dyes and antiseptics; (also) any substituted derivative of this.Acridine has a molecule consisting of two benzene rings fused to a central pyridine ring. Formula: C₁₃H₉N.

ΘΚΠ

the world > matter > chemistry > organic chemistry > organic compounds > [noun] > heterocyclic compounds > other heterocyclic compounds

alloxan1839

piperidine1854

valerin1866

acridine1870

piperidia1871

kairoline1883

quinoxaline1884

pyrimidine1885

pyrazolone1887

quinazoline1887

pyrazine1888

acridone1892

phthalazine1893

pyridazine1894

nitron1906

pyrrolizidine1939

1870 Chem. News 14 Oct. 192/1 The authors discovered, while engaged in purifying crude anthracen, a new substance, which, on account of its biting action when brought into contact with the skin, they have called acridine.

1922 J. J. Sudborough Bernthsen's Text-bk. Org. Chem. (new ed.) xxxviii. 582 Acridine, like anthracene, is a chromogene.

1990 Mutagenesis 5 531/1 While these compounds are acridines, they carry an alkylating (nitrogen mustard) substituent.

2004 Proteomics Weejly (Nexis) 12 Jan. 57 3,6-diamino substitution on the acridine ring greatly improves parasiticidal activity.

Compounds

acridine orange n. a fluorescent dye derived from acridine which binds to nucleic acids, now chiefly used in diagnostic and experimental microbiology.Systematic name: N,N,N′,N′-tetramethylacridine-3,6-diamine; C₁₇H₁₉N₃.

ΚΠ

1891 Jrnl. Soc. Chem. Industry 28 Feb. 135/1 Acridine Orange..dyes cotton mordanted with tannin and tartar emetic a fast and brilliant orange.

1953 Amer. Naturalist 87 296 Acridine orange is undoubtedly mutagenic.

2000 S. Garfield Mauve 189 We have also used acridine orange for staining and diagnosing malaria in the past.

This entry has been updated (OED Third Edition, December 2011; most recently modified version published online December 2021).

单词	acridine
释义	acridinen. Brit. /ˈakrᵻdiːn/, /ˈakrᵻdʌɪn/, U.S. /ˈækrəˌdin/, /ˈækrəd(ə)n/ Origin: Formed within English, by derivation; modelled on a German lexical item. Etymons: acrid adj., -idine suffix. Etymology: < acr- (in acrid adj.) + -idine suffix, after German Acridin (C. Graebe and H. Caro 1870, in Berichte der Deutsch. Chem. Ges. 3 746). Chemistry. A crystalline heterocyclic compound which occurs naturally in coal tar, is an irritant of the skin and mucous membranes, and is used in the manufacture of dyes and antiseptics; (also) any substituted derivative of this.Acridine has a molecule consisting of two benzene rings fused to a central pyridine ring. Formula: C₁₃H₉N. ΘΚΠ the world > matter > chemistry > organic chemistry > organic compounds > [noun] > heterocyclic compounds > other heterocyclic compounds alloxan1839 piperidine1854 valerin1866 acridine1870 piperidia1871 kairoline1883 quinoxaline1884 pyrimidine1885 pyrazolone1887 quinazoline1887 pyrazine1888 acridone1892 phthalazine1893 pyridazine1894 nitron1906 pyrrolizidine1939 1870 Chem. News 14 Oct. 192/1 The authors discovered, while engaged in purifying crude anthracen, a new substance, which, on account of its biting action when brought into contact with the skin, they have called acridine. 1922 J. J. Sudborough Bernthsen's Text-bk. Org. Chem. (new ed.) xxxviii. 582 Acridine, like anthracene, is a chromogene. 1990 Mutagenesis 5 531/1 While these compounds are acridines, they carry an alkylating (nitrogen mustard) substituent. 2004 Proteomics Weejly (Nexis) 12 Jan. 57 3,6-diamino substitution on the acridine ring greatly improves parasiticidal activity. Compounds acridine orange n. a fluorescent dye derived from acridine which binds to nucleic acids, now chiefly used in diagnostic and experimental microbiology.Systematic name: N,N,N′,N′-tetramethylacridine-3,6-diamine; C₁₇H₁₉N₃. ΚΠ 1891 Jrnl. Soc. Chem. Industry 28 Feb. 135/1 Acridine Orange..dyes cotton mordanted with tannin and tartar emetic a fast and brilliant orange. 1953 Amer. Naturalist 87 296 Acridine orange is undoubtedly mutagenic. 2000 S. Garfield Mauve 189 We have also used acridine orange for staining and diagnosing malaria in the past. This entry has been updated (OED Third Edition, December 2011; most recently modified version published online December 2021). < n.1870
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