alkaptonuricadj.n.
/alˌkaptəˈnjʊərɪk/, U.S. /ælˌkæptəˈn(j)ʊrɪk/ Medicine.
A. adj.
Affected with alkaptonuria; characteristic of alkaptonuria.
ΘΚΠ
the world > health and disease > ill health > a disease > disorders of internal organs > urinary disorders > [adjective] > other substances in urine
saccharine1845
albuminuric1847
urrhodinic1886
loaded1898
alkaptonuric1899
pentosuric1906
proteinuric1921
natriuretic1953
1899 A. E. Garrod in Jrnl. Physiol. 23 512 The urine of an alkaptonuric individual.
1949 Lancet 18 June 1044/2 Ascorbic acid and homogentisic acid from alcaptonuric urine produce a black spot immediately in the cold.
1984 L. W. Browder Developmental Biol. (ed. 2) i. 22 The disease is detected early in life, since the urine of alkaptonuric babies stains their diapers black.
1997 R. Porter Greatest Benefit to Mankind xviii. 587 He noted that among four families in which unaffected parents had produced alkaptonuric offspring, three of the parental pairs were first cousins.
B. n.
An individual affected with alkaptonuria.
ΘΚΠ
the world > health and disease > ill health > a disease > disorders of internal organs > urinary disorders > [noun] > other substances in urine > person
alkaptonuric1902
pentosuric1906
1902 A. E. Garrod in Lancet 13 Dec. 1616/2 One family contained four alkaptonurics.
1949 H. W. C. Vines Green's Man. Pathol. (ed. 17) iii. 57 A black melanin pigment is formed which in ochronosis results in pigmentation of the cartilages of the body, and in alkaptonurics causes darkening of the urine on exposure to air.
1989 Human Pathol. 20 43 Renal calculi are common in alkaptonurics.
2002 Molecular Genetics & Metabolism 75 358/1 The coefficient of selection was very low..and did not confirm selective advantage or disadvantage in alkaptonurics.
This entry has been updated (OED Third Edition, September 2009; most recently modified version published online December 2021).
<
adj.n.1899