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单词 alkapton
释义

alkaptonn.

Brit. /alˈkaptɒn/, U.S. /ælˈkæpˌtɑn/, /ælˈkæpt(ə)n/
Forms: 1800s– alcapton, 1800s– alkapton.
Origin: A borrowing from German. Etymons: German Alkapton, Alcapton.
Etymology: < German Alkapton, †Alcapton (C. Boedeker 1859, in Zeitschrift f. rationelle Medicin 7 139) < al- (in Alkali alkali n.) + ancient Greek κάπτον , neuter present participle of κάπτειν to swallow greedily (see capsicum n.); see quot. 1860 for the semantic motivation of the name.
Medicine. Now chiefly historical.
An acidic substance, later identified with homogentisic acid, which is excreted by people with alkaptonuria and causes their urine, left standing, to turn dark through oxidation.Homogentisic acid is 2,5-dihydroxyphenylacetic acid; C6H4(OH)2COOH.
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the world > matter > chemistry > organic chemistry > acids obtained from animals > [noun] > in urine > miscellaneous others
hippuric acid1831
alkapton1860
hydurilic acid1865
toluric acid1868
kynurenic acid1872
mercapturic acid1879
phenylpyruvic acid1887
EDTA1950
1860 E. A. Parkes Composition of Urine 193 As the alkaline solution eagerly absorbed oxygen, he called it ‘alcapton’ (from the Arabic alkali and the Greek κάπτειν, to swallow eagerly).
1885 Lancet 7 Mar. 433/2 Pyrocatechin, which he believes to be identical with Bödecker's alkapton.
1909 Biol. Bull. 16 325 In the condition known as ‘alkaptonuria’ the alkapton acids—uroleuic and homogentisic—appear in the urine.
1977 T. I. Storer et al. Elements Zool. (ed. 4) xi. 165/2 An individual suffering from alkaptonuria..lacks the enzyme to oxidise alkapton.
1998 Jrnl. Amer. Acad. Dermatol. 39 535/1 The HGA or ‘alkapton’ is 2, 5-hydroquinone acetic acid and is excreted into the urine.
This entry has been updated (OED Third Edition, September 2009; most recently modified version published online December 2021).
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n.1860
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