单词 | itim | ||||||||||||
释义 | ITIMITIMA short sequence of amino acids [(ILV)-x-x-Y-x-(LV)] found in the cytoplasmic tail of inhibitory immune receptors—e.g., platelet-endothelial cell adhesion molecule (1–PECAM-1/CD31). Phosphorylation of tyrosine residues in ITIMs is an important signalling mechanism which regulates immune cell activation and possibly other cellular processes.ITIM
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