phentolaminen.

Brit.

/fɛnˈtɒləmiːn/, U.S.

/fɛnˈtɑləˌmin/

Origin: Formed within English, by compounding. Etymons: phen- comb. form, toluidine n., amine n.

Etymology: < phen- comb. form + tol- (in toluidine n.) + amine n., representing components of the molecular structure.

Pharmacology.

An alpha blocker used as a vasodilator, esp. in the management of hypertensive crises caused by phaeochromocytoma.Chemical name: 2-[N-(m-hydroxyphenyl)-p-toluidinomethyl]imidazoline, C₁₇H₁₉N₃O.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for blood-pressure disorders

Neo-Synephrine1934

Priscol1938

phenylephrine1947

hexamethonium1949

Priscoline1949

methonium1950

hydralazine1952

phentolamine1953

methyldopa1954

pentolinium1954

mecamylamine1955

hydrochlorothiazide1958

pempidine1958

guanethidine1959

hydroflumethiazide1959

thiazide1959

pheniprazine1960

pargyline1961

vasodepressor1961

alpha blocker1965

clonidine1969

prazosin1970

timolol1973

1953 Jrnl. Amer. Med. Assoc. 15 Aug. 1533/2 Phentolamine hydrochloride, a salt of phentolamine base, is suitable for oral administration and acts as a potent adrenergic blocking agent, producing adrenolytic and sympatholytic effects.

1961 L. C. Martin Clin. Endocrinol. (ed. 3) vi. 182 Phentolamine is the most reliable of the adrenolytic substances both for diagnosis of phæochromocytoma and for use during its removal.

1972 Materials & Technol. V. xxi. 810 Alpha receptor blockers such as tolazoline may be used in the treatment of peripheral blood vessel spasm, while phentolamine is used to treat hypertensive (high blood pressure) crises.

1998 New Scientist 19 Dec. 24/3 Phentolamine..has been shown to help up to forty per cent of men with mild to moderate impotence, with nasal congestion as the main side effect.

This entry has been updated (OED Third Edition, December 2005; most recently modified version published online March 2022).

单词	phentolamine
释义	phentolaminen. Brit. /fɛnˈtɒləmiːn/, U.S. /fɛnˈtɑləˌmin/ Origin: Formed within English, by compounding. Etymons: phen- comb. form, toluidine n., amine n. Etymology: < phen- comb. form + tol- (in toluidine n.) + amine n., representing components of the molecular structure. Pharmacology. An alpha blocker used as a vasodilator, esp. in the management of hypertensive crises caused by phaeochromocytoma.Chemical name: 2-[N-(m-hydroxyphenyl)-p-toluidinomethyl]imidazoline, C₁₇H₁₉N₃O. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for blood-pressure disorders Neo-Synephrine1934 Priscol1938 phenylephrine1947 hexamethonium1949 Priscoline1949 methonium1950 hydralazine1952 phentolamine1953 methyldopa1954 pentolinium1954 mecamylamine1955 hydrochlorothiazide1958 pempidine1958 guanethidine1959 hydroflumethiazide1959 thiazide1959 pheniprazine1960 pargyline1961 vasodepressor1961 alpha blocker1965 clonidine1969 prazosin1970 timolol1973 1953 Jrnl. Amer. Med. Assoc. 15 Aug. 1533/2 Phentolamine hydrochloride, a salt of phentolamine base, is suitable for oral administration and acts as a potent adrenergic blocking agent, producing adrenolytic and sympatholytic effects. 1961 L. C. Martin Clin. Endocrinol. (ed. 3) vi. 182 Phentolamine is the most reliable of the adrenolytic substances both for diagnosis of phæochromocytoma and for use during its removal. 1972 Materials & Technol. V. xxi. 810 Alpha receptor blockers such as tolazoline may be used in the treatment of peripheral blood vessel spasm, while phentolamine is used to treat hypertensive (high blood pressure) crises. 1998 New Scientist 19 Dec. 24/3 Phentolamine..has been shown to help up to forty per cent of men with mild to moderate impotence, with nasal congestion as the main side effect. This entry has been updated (OED Third Edition, December 2005; most recently modified version published online March 2022). < n.1953
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