peptidomimeticn.adj.
/ˌpɛptᵻdə(ʊ)mᵻˈmɛtɪk/, /pɛpˌtʌɪdə(ʊ)mᵻˈmɛtɪk/, U.S. /ˈˌpɛptədoʊməˈmɛdɪk/ Pharmacology.
A. n.
A biologically active compound, esp. a manufactured one, that resembles a natural peptide such as a cytokine or chemokine.
ΚΠ
1987 Science 21 Aug. 929 (advt.) Selected candidate will work in a drug discovery program dedicated to development of therapeutically useful peptidomimetics.
2000 Proc. National Acad. Sci. U.S.A. 97 9373/2 To date, most Src SH2 inhibitors have been phosphopeptides..or peptidomimetics.
B. adj.
Of, relating to, or involving peptidomimetics; designating a peptidomimetic.
ΚΠ
1988 Drug Intelligence & Clin. Pharmacy 22 154 (title) Octreotide: entering the new era of peptidomimetic therapy.
1998 Chem. in Brit. Oct. 48/1 The success of this approach has been a great stimulus for peptidomimetic chemistry.
2003 Drugs 63 1611 Tipranavir is a..non-peptidic HIV-1 protease inhibitor with a markedly improved resistance profile compared with traditional, peptidomimetic protease inhibitors.
This is a new entry (OED Third Edition, September 2005; most recently modified version published online March 2022).
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