| 释义 |
Marezine Pharm.|ˈmærəziːn|
Also marezine.
[f. mare- + piperazine.]
1-Methyl-4-α-phenylpiperazine hydrochloride, C18H22N2.HCl, used in the form of tablets as an anti-emetic, esp. for the prevention and treatment of motion sickness. In the British Pharmacopœia called cyclizine hydrochloride.
Marezine is registered as a proprietary name in the U.S.
1952Official Gaz. (U.S. Patent Office) 23 Dec. 1007/1 Burroughs Wellcome & Co... Marezine for medicinal preparations intended for use in the prevention or treatment of allergies, motion sickness, nausea and vomiting in pregnancy, or nausea due to other causes. 1954Jrnl. Pharmacol. & Exper. Therap. CXII. 297 (heading) Pharmacologic properties of cyclizine hydrochloride (marezine). 1965Economist 6 Nov. 615/2 The Food and Drug Administration announced last week that three anti-histamines—Bonine, Marezine and Cyclizine—which are used to combat nausea, including morning sickness, must carry a warning on their labels that, if taken by a pregnant woman, they may harm her unborn child. 1969Guardian 21 July 9/2 Each [astronaut]..carries..45 milligrams of marezine for motion sickness. |