| 释义 |
urokinase Biochem. and Pharm.|jʊərəʊˈkaɪneɪz|
[f. uro-1 + kinase.]
An enzyme which catalyses the conversion of plasminogen to plasmin and is used in the treatment of blood clots.
1952G. W. Sobel et al. in Amer. Jrnl. Physiol. CLXXI. 768/2 Normal human and dog urine contains..a potent activator of profibrinolysin (plaminogen). The activator..we have designated urokinase. 1977Daily Colonist (Victoria, B.C.) 23 Oct. 10/5 Urokinase is used in the treatment of blood clots and scientists said it has the potential of preventing 50,000 deaths per year in the United States alone. 1983Davies & McNicol in Oxf. Textbk. Med. II. xix. 132/2 Urokinase is produced naturally by cells in the kidney and is present in human urine, probably to aid maintenance of ureteric patency. |