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单词 tata box
释义

TATA boxn.

Brit. /ˈtɑːtɑː ˌbɒks/, U.S. /ˈtɑˌtɑ ˌbɑks/
Origin: Formed within English, by clipping or shortening. Etymon: box n.2
Etymology: < TATA, shortened < TATAAA, the repeated initials of the bases thymine and adenine in the consensus sequence of this DNA element + box n.2
Genetics.
A conserved DNA element which forms part of the promoter (promoter n. 4c) of many eukaryotic genes. Also called Hogness box.
ΚΠ
1980 Nature 20 Nov. 210/1 The sequence is invariably AT rich and is most commonly known as the TATA (tar-tar) box but at other times as the Hogness box.
1993 Cell 73 386/2 The reporter gene was chloramphenicol acetyl transferase (CAT), controlled by a synthetic promoter comprising two GAL4 operators linked to a TATA box.
2006 Jrnl. Cell Biol. 172 122/1 There is an increasing number of genes that are controlled by the core promoter sequence, including the TATA box (minimal promoter).
This is a new entry (OED Third Edition, November 2010; most recently modified version published online March 2022).
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n.1980
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