organificationn.
/ɔːˌɡanᵻfᵻˈkeɪʃn/, U.S. /ɔrˌɡænəfəˈkeɪʃ(ə)n/ Chiefly Physiology.
Incorporation of a chemical element into an organic compound; spec. incorporation of iodine into a thyroid hormone.
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organification1937
1937 Nature 15 May 836/1 (heading) Rate of ‘organification’ of phosphorus in animal tissues.
1966 G. P. Wright & W. S. Symmers Systemic Pathol. II. xxxi. 1099/1 Thiocarbamide and aniline derivatives..impair organification of iodine in the thyroid.
1989 Biotropica 21 92 The potential threat of Hg contamination in this area..is the possibility of Hg undergoing organification in natural waters to alkyl-Hg compounds, in particular to monomethyl mercury.
1994 D. Tulchinsky & A. B. Little Maternal–Fetal Endocrinol. (ed. 2) viii. 132/2 Trapping of iodide from plasma is followed by organification of the iodide, i.e. iodination of tyrosine residues of the thyroglobulin molecule.
2000 Endocrinology 141 839 The thyroid disease typically develops around puberty and is associated with a mild organification defect, characterized by an inappropriate discharge of iodide upon perchlorate stimulation.
This entry has been updated (OED Third Edition, September 2004; most recently modified version published online March 2022).
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n.1937