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单词 motor neuron disease
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motor neuron disease
motor neuron disease n. any of several, often hereditary, diseases characterized by degeneration of motor neurons and progressive weakness and atrophy of muscles; abbreviated MND.
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1933 W. R. Brain Dis. Nerv. Syst. ix. 497 Amyotrophic lateral sclerosis. Synonyms: Progressive muscular atrophy; progressive bulbar palsy; motor neurone disease; chronic poliomyelitis.
1958 J. G. Greenfield et al. Neuropathol. ix. 545 The name amyotrophic lateral sclerosis..is more correct than the suggested alternative motor neurone disease, since degeneration is not confined to motor neurones.
1974 R. Passmore & J. S. Robson Compan. Med. Stud. III. xxxiv. 53/2 Motor neurone disease may present with any combination of upper and lower motor neurone signs.
1990 Brain 113 305 We..studied a large series of cases with motor neuron disease (amyotrophic lateral sclerosis; ALS) in which degeneration of the corticospinal tracts is particularly well seen.
1996 Pract. Gardening June 27/1 Jimmy suffered from motor neurone disease (MND), a progressive illness which eventually rendered him immobile.
extracted from motorn.adj.
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