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单词 misoprostol
释义

misoprostoln.

Brit. /mʌɪsə(ʊ)ˈprɒstɒl/, U.S. /ˌmaɪsoʊˈprɑstɑl/
Origin: Formed within English, by derivation. Etymons: methyl n., iso- comb. form, prostaglandin n., -ol suffix.
Etymology: < m (in methyl n.) + iso- comb. form + prost- (in prostaglandin n.) + -ol suffix.
Pharmacology.
A synthetic analogue of prostaglandin E1, used to treat peptic ulcer disease and to induce labour; (±)-15-deoxy-(16RS)-16-hydroxy-16-methyl-PGE1 methyl ester, C22H38O5.
ΚΠ
1982 Approved Names 1981 (Brit. Pharmacopœia Comm.) Suppl. iii Misoprostol... (±)-Methyl 7-[(1R, 2R, 3R)-3-hydroxy-2-[(E)-(4RS)-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl] heptanoate.
1987 Today's Health Apr. 53/2 Misoprostol (brand name Cytotec) has a combined action against ulcers; working to both inhibit gastric acid secretion and also protect the mucosal lining of the stomach and intestines.
1990 L. H. Tribe Abortion 219 One drug already licensed..misoprostol, is known to cause changes in the muscle tone of the uterus that trigger miscarriages.
2000 Acta Obstetr. & Gynecol. Scand. 79 1065 Misoprostol, a prostaglandin E1 analog registered for the prevention of gastric ulcers in NSAID-drug users, has been reported to be more effective for labor induction than the standard prostaglandin.
This is a new entry (OED Third Edition, June 2002; most recently modified version published online March 2022).
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n.1982
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