magaininn.

Brit.

/məˈɡʌɪnɪn/,

/məˈɡeɪnɪn/, U.S.

/məˈɡaɪnᵻn/,

/məˈɡeɪnᵻn/

Origin: A borrowing from Hebrew, combined with an English element. Etymons: Hebrew māgēn , -in suffix¹.

Etymology: < Hebrew māgēn shield (see quot. 1987) + -in suffix¹.

Biochemistry.

Any of a group of peptides with antimicrobial properties that resemble those first identified in the skin of the African clawed frog, Xenopus laevis.

ΘΚΠ

the world > life > biology > substance > process stimulators or inhibitors > antibiotic > [noun]

actinomycin1940

claviformin1942

antibiotic1944

bacteriocin1954

gentamicin1963

rishitin1968

magainin1987

1987 M. Zasloff in Proc. National Acad. Sci. U.S.A. 86 5450/2 The two components with highest specific activity were seen to be related but distinctly different peptides... They have been designated ‘magainins’ (derived from the Hebrew word ‘magain’ meaning ‘shield’), reflecting their possible function as an antimicrobial shield.

1990 Biochem. Pharmacol. 39 626/1 To simplify matters for this review, the umbrella term magainins or ‘magainin family of molecules’ refers to: Magainins 1 and 2; closely related chemical congeners possessing similar antimicrobial and probable host defense functions (e.g. PGLa, XPF, also originally described in frog skin); amphipathic or natural synthetic homologs which also produce ion channels in cell membranes resulting in antimicrobial or host defense activity.

1991 Proc. National Acad. Sci. U.S.A. 88 3793/1 Synthetic magainins A, B, and G..were at least 9-fold more potent than the natural magainin 2 structure.

1998 Biochemistry 37 11856 Magainin 2, an antimicrobial peptide from the Xenopus skin, kills bacteria by permeabilizing the cell membranes.

This is a new entry (OED Third Edition, March 2000; most recently modified version published online March 2022).

单词	magainin
释义	magaininn. Brit. /məˈɡʌɪnɪn/, /məˈɡeɪnɪn/, U.S. /məˈɡaɪnᵻn/, /məˈɡeɪnᵻn/ Origin: A borrowing from Hebrew, combined with an English element. Etymons: Hebrew māgēn , -in suffix¹. Etymology: < Hebrew māgēn shield (see quot. 1987) + -in suffix¹. Biochemistry. Any of a group of peptides with antimicrobial properties that resemble those first identified in the skin of the African clawed frog, Xenopus laevis. ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > antibiotic > [noun] actinomycin1940 claviformin1942 antibiotic1944 bacteriocin1954 gentamicin1963 rishitin1968 magainin1987 1987 M. Zasloff in Proc. National Acad. Sci. U.S.A. 86 5450/2 The two components with highest specific activity were seen to be related but distinctly different peptides... They have been designated ‘magainins’ (derived from the Hebrew word ‘magain’ meaning ‘shield’), reflecting their possible function as an antimicrobial shield. 1990 Biochem. Pharmacol. 39 626/1 To simplify matters for this review, the umbrella term magainins or ‘magainin family of molecules’ refers to: Magainins 1 and 2; closely related chemical congeners possessing similar antimicrobial and probable host defense functions (e.g. PGLa, XPF, also originally described in frog skin); amphipathic or natural synthetic homologs which also produce ion channels in cell membranes resulting in antimicrobial or host defense activity. 1991 Proc. National Acad. Sci. U.S.A. 88 3793/1 Synthetic magainins A, B, and G..were at least 9-fold more potent than the natural magainin 2 structure. 1998 Biochemistry 37 11856 Magainin 2, an antimicrobial peptide from the Xenopus skin, kills bacteria by permeabilizing the cell membranes. This is a new entry (OED Third Edition, March 2000; most recently modified version published online March 2022). < n.1987
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