hemizygousadj.

/hɛmɪˈzʌɪɡəs/

Etymology: < hemi- prefix + -zygous (in homozygous adj. at homozygote n. Derivatives).

Biology.

Having a single unpaired allele at a particular genetic locus, as at all the loci in an XO pair of sex-chromosomes and some of the loci in an XY pair, rather than having two paired alleles, one on each homologous chromosome, as normally occurs in a diploid.

ΘΚΠ

the world > life > biology > biological processes > genetic activity > genetic components > [adjective] > allele > condition with respect to

heterozygous1902

homozygous1902

nulliplex1911

simplex1911

hemizygous1921

quadruplex1923

triallelic1944

heterogenic1947

homogenic1947

null1955

1921 W. A. Lippincott in Amer. Naturalist 55 570 I should like to suggest the noun hemizeuxis (a half yoking) and the corresponding adjective hemizygous (half yoked). Should such a suggestion prove acceptable there would be the three adjective series: homozygous, heterozygous, and hemizygous, referring to the three possible conditions with respect to any single gene, namely, ‘like mates’, ‘differing mates’, and ‘no mate’.

1935 H. J. Muller in Jrnl. Genetics XXX. 407 The terms ‘hemizygous’ and ‘hemizygote’ (Serebrovsky) refer to the condition of being haploid for a given gene when the genome as a whole is diploid; its usual usage is in connection with sex-linked genes in the sex in which they are haploid.

1939 C. H. Waddington Introd. Mod. Genetics ii. 62 Muller has suggested that it would be better to speak of factors in haploid organisms such as male bees as hemizygous; and this word can also be used for factors (e.g. in an unpaired X chromosome) for which there is no allelomorph in a normal diploid.

1961 Lancet 16 Sept. 626/2 In a hemizygous XO female, a recessive gene could express itself as in a heterozygous XY male.

1965 J. A. Serra Mod. Genetics I. iv. 109 The yellow-black pair of alleles in cats producing either yellow or black hemizygous males but giving patched black and yellow or ‘tortoise-shell’ females when these are heterozygous.

Derivatives

hemiˈzygote n. a hemizygous organism.

ΘΚΠ

the world > life > biology > biological processes > genetic activity > genetic components > [noun] > allele > condition with respect to > individual

heterozygote1902

homozygote1902

hemizygote1935

1935 H. J. Muller in Jrnl. Genetics XXX. 407 The normal gene, although apparently quite dominant to white and to the other mutants, must in reality be incompletely so, and the heterozygotes, being like uncompensated hemizygotes, must have a definitely lower average survival rate.

hemizyˈgotic adj. hemizygous.

ΚΠ

1965 J. A. Serra Mod. Genetics I. iv. 103 The genes for haemophilia and for colour-blindness have no allele in the Y chromosome, that is the males are hemizygotic for these factors.

hemiˈzygously adv. in a manner characteristic of a hemizygote.

ΚΠ

1965 J. A. Serra Mod. Genetics I. iv. 111 Such a character is transmitted from father to son and because there is no corresponding allele in the X chromosome, it manifests itself hemizygously.

This entry has not yet been fully updated (first published 1976; most recently modified version published online June 2018).

单词	hemizygous
释义	hemizygousadj. /hɛmɪˈzʌɪɡəs/ Etymology: < hemi- prefix + -zygous (in homozygous adj. at homozygote n. Derivatives). Biology. Having a single unpaired allele at a particular genetic locus, as at all the loci in an XO pair of sex-chromosomes and some of the loci in an XY pair, rather than having two paired alleles, one on each homologous chromosome, as normally occurs in a diploid. ΘΚΠ the world > life > biology > biological processes > genetic activity > genetic components > [adjective] > allele > condition with respect to heterozygous1902 homozygous1902 nulliplex1911 simplex1911 hemizygous1921 quadruplex1923 triallelic1944 heterogenic1947 homogenic1947 null1955 1921 W. A. Lippincott in Amer. Naturalist 55 570 I should like to suggest the noun hemizeuxis (a half yoking) and the corresponding adjective hemizygous (half yoked). Should such a suggestion prove acceptable there would be the three adjective series: homozygous, heterozygous, and hemizygous, referring to the three possible conditions with respect to any single gene, namely, ‘like mates’, ‘differing mates’, and ‘no mate’. 1935 H. J. Muller in Jrnl. Genetics XXX. 407 The terms ‘hemizygous’ and ‘hemizygote’ (Serebrovsky) refer to the condition of being haploid for a given gene when the genome as a whole is diploid; its usual usage is in connection with sex-linked genes in the sex in which they are haploid. 1939 C. H. Waddington Introd. Mod. Genetics ii. 62 Muller has suggested that it would be better to speak of factors in haploid organisms such as male bees as hemizygous; and this word can also be used for factors (e.g. in an unpaired X chromosome) for which there is no allelomorph in a normal diploid. 1961 Lancet 16 Sept. 626/2 In a hemizygous XO female, a recessive gene could express itself as in a heterozygous XY male. 1965 J. A. Serra Mod. Genetics I. iv. 109 The yellow-black pair of alleles in cats producing either yellow or black hemizygous males but giving patched black and yellow or ‘tortoise-shell’ females when these are heterozygous. Derivatives hemiˈzygote n. a hemizygous organism. ΘΚΠ the world > life > biology > biological processes > genetic activity > genetic components > [noun] > allele > condition with respect to > individual heterozygote1902 homozygote1902 hemizygote1935 1935 H. J. Muller in Jrnl. Genetics XXX. 407 The normal gene, although apparently quite dominant to white and to the other mutants, must in reality be incompletely so, and the heterozygotes, being like uncompensated hemizygotes, must have a definitely lower average survival rate. hemizyˈgotic adj. hemizygous. ΚΠ 1965 J. A. Serra Mod. Genetics I. iv. 103 The genes for haemophilia and for colour-blindness have no allele in the Y chromosome, that is the males are hemizygotic for these factors. hemiˈzygously adv. in a manner characteristic of a hemizygote. ΚΠ 1965 J. A. Serra Mod. Genetics I. iv. 111 Such a character is transmitted from father to son and because there is no corresponding allele in the X chromosome, it manifests itself hemizygously. This entry has not yet been fully updated (first published 1976; most recently modified version published online June 2018). < adj.1921
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