transitive. To put forth, exert, use (one's diligence, endeavour, etc.) in effecting something.

To direct (one's mind, intention, or will) to the consideration or performance of something. Now rare.

In various figurative uses. To take to one's heart, cultivate (a virtue, disposition, etc.). Obsolete.

transitive. To give or devote (a faculty) assiduously to. Also with infinitive and without complement.