| 释义 |
nephrosis Path.|nɛˈfrəʊsɪs|
Pl. -oses.
[f. nephro- + -osis.]
†a. (See quot.) Obs. exc. as in b.
1900Dorland Med. Dict. 428/1 Nephrosis, any disease of the kidney.
b. [a. G. nephrose (F. Müller 1905, in Verhandl. d. Deut. Path. Ges. IX. 65).] A syndrome characterized by œdema, albuminuria, a fall in the plasma albumin, and usu. an increase in the blood cholesterol, formerly attributed to degeneration of the renal tubules but now known to arise from increased permeability to protein of the glomerular capillary basement membranes.
1916L. F. Barker Monogr. Med. III. 954 (heading) Toxic degenerative tubular nephropathies without marked glomerular involvement (the so-called nephroses). 1926H. Elwyn Nephritis v. 74 Tubular degenerations occurring in the course of other diseases, when presenting definite renal symptoms, may be similarly designated by the term nephrosis of the particular disease in which they occur. 1929Amer. Jrnl. Path. V. 619 Lipoid nephrosis is to be regarded as a form of glomerulonephritis in which the glomeruli are damaged but their capillaries are only partially obstructed. 1946E. T. Bell Renal Dis. vi. 217 The tubular atrophy in lipoid nephrosis is due to disuse and anemia. 1973J. Brod Kidney xix. 405/1 Unlike glomerulonephritis pure nephrosis is encountered mostly in children under 5 years of age. |