| 释义 |
haplotype, n.
Brit. |ˈhaplə(ʊ)tʌɪp|, U.S. |ˈhæpləˌtaɪp|
[‹ haplo- comb. form + -type suffix.]
1. Biol. A species taken as the type species of a genus because no other was originally included in the genus. rare.
1914O. F. Cook in Amer. Naturalist 48 314 Haplotype.—Type by single reference. A single species referred to a genus at the original place of publication, and on this account accepted as the type.
2. Genetics. The particular combination of alleles present in a specific region of a chromosome; (originally) spec. that of the major hisocompatability complex.
1967R. Ceppellini et al. in E. S. Curtoni et al. Histocompatibility Testing 1967 165/1 If a new term can be introduced without increasing confusion, it is suggested to substitute phenogroup with haplotype (haploid, from ἁπλóος, single); in fact the name should convey the concept that the haplotype is not an observed phene and corresponds to the product of a single gene dose. 1968Lancet 6 Apr. 724/1 We have tried to analyse the HL-A haplotypes of the matings by tissue typing them and their children. 1989E. Lawrence Guide Mod. Biol. xii. 431 Each person (or animal) inherits a set (a haplotype) of MHC [major histocompatibility complex] specificities from their father and another from their mother. 2002Science 20 Dec. 2299/2 Geneticists are pinning their hopes for progress on the HapMap, a major multiyear undertaking to map variation in stretches of human DNA called haplotypes.
Derivatives. haplotypic adj.
1914O. F. Cook in Amer. Naturalist 48 314 A genus proposed with reference to a single species is *haplotypic. 1977Evolution 31 778/1 Haplotypic diversity was highest in the Rio Mayo where recurrent hybrid syntheses are possible. 2003Theoret. & Appl. Genetics 1071123 The distribution of haplotypic variation in P[inus]canariensis suggested the colonization of western Canary Islands from a single continental source located close to the Mediterranean Basin. |