释义 |
microsatellite instability
microsatellite instability An abnormality in a DNA sequence in which a microsatellite (repeating 2–6 nucleotides) found in intronic DNA is either longer or shorter than normal, which is most commonly due to defective mismatch repair.microsatellite instability A detectable change in the number of DNA repeat sequences that may lead to mutations in mismatch-repair genes.See MI See MSI |