inactivated poliovirus vaccine


po·li·o·vi·rus vac·cines

1. inactivated poliovirus vaccine (IPV), an aqueous suspension of inactivated strains of poliomyelitis virus (types 1, 2, and 3) used by injection; has largely been replaced by the oral vaccine; 2. oral poliovirus vaccine (OPV), an aqueous suspension of live, attenuated strains of poliomyelitis virus (types 1, 2, and 3) given orally for active immunization against poliomyelitis. Synonym(s): poliomyelitis vaccines

inactivated poliovirus vaccine

, poliovirus vaccine, inactivatedAn injectable vaccine made from three types of inactivated polioviruses. Developed by Jonas E. Salk, it was the first successful vaccine against poliomyelitis and is now the only polio vaccine administered in the U.S. Synonym: Salk vaccine

Infants should be given three doses, the first at 2 months of age, followed by two more doses at 8-week intervals. A fourth dose should be given at age 18 months unless poliomyelitis is endemic in the area, in which case the fourth dose is given 6 to 12 months after the third. Additional doses are recommended prior to school entry and then every 5 years until age 18.

See also: vaccine