transitive. With animate subject: to cause trouble or harm to, to afflict. Obsolete.

transitive. Of an illness, sensation, or any other force or agency: to act on, affect, or attack (a person or animal), esp. suddenly; to take hold…

Of sickness, etc.: to come upon (a person or persons), to assail or afflict. Frequently in passive and const. with or by.

Of disease or ailment: to cause bodily derangement, pain, or inconvenience to; to afflict; sometimes in weakened sense, to affect. (Often in passive…

transitive. Esp. of disease, pain, etc.: to affect with physical discomfort, distress, or suffering; to afflict.

transitive. To ‘take hold of’ or affect suddenly or unexpectedly. Chiefly passive. To be seized with (or of) a desire, emotion, etc., a disease or…

To afflict or visit (a person) with sickness or harm. Obsolete.

To touch, strike, or seize upon, as a disease or other bodily or mental affection; to affect.

transitive. To afflict with heartburn (heartburn, n. 2). Also figurative.

transitive. Of a disease: to afflict or affect, esp. recurrently. Also figurative. Obsolete.

To be amiss with, to ail.

transitive. Of a disease, etc.: to affect; to infect. Obsolete.

transitive. To affect badly or injuriously.

To seize.

transitive. To affect with disease or sickness; to make an invalid; to ‘lay up’ or disable by illness or injury. (Chiefly in passive.)