trastuzumabn.

Brit.

/ˌtrɑːˈstuːzuːmab/,

/ˌtraˈstuːzuːmab/, U.S.

/ˌtræˈstuzumæb/

Origin: Formed within English, by compounding. Etymons: English trastuz- , human adj., English monoclonal antibody.

Etymology: < trastuz- (origin unknown) +-u- (in human adj.) + -mab , representing monoclonal antibody ( < monoclonal adj. + antibody n.).

Pharmacology.

A drug consisting of a preparation of humanized monoclonal antibodies directed against a cell surface receptor (human epidermal growth factor receptor 2; Her2) which contributes to the growth of some breast cancers, used in the treatment of such cancers.A proprietary name for this drug is Herceptin.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for cancer or leukemia

amethopterin1948

Myleran1952

Laetrile1953

thioguanine1953

thioTEPA1953

mercaptopurine1954

methotrexate1955

busulfan1956

chlorambucil1956

cyclophosphamide1960

vinblastine1962

vincristine1962

levamisole1969

vinca alkaloid1970

doxorubicin1971

tamoxifen1972

Airol1974

trastuzumab1997

thiotepa-

1997 Business Wire (Nexis) 22 Dec. Genentech, based in South San Francisco, California, Friday announced favorable preliminary results from a Phase III trial of its trastuzumab (Herceptin) anti-HER2 monoclonal antibody in women with metastatic breast cancer who overexpress the HER2 oncogene.

1998 Lancet 10 Oct. 1205/1 On Sept. 25, the US FDA approved the first monoclonal antibody for breast cancer, Genentech's trastuzumab.

2008 Atlantic Monthly July 81/2 Breast-cancer patients with one of the two forms of the gene HER-2 responded differently to the new cancer drug trastuzumab (Herceptin).

This is a new entry (OED Third Edition, November 2010; most recently modified version published online March 2022).

单词	trastuzumab
释义	trastuzumabn. Brit. /ˌtrɑːˈstuːzuːmab/, /ˌtraˈstuːzuːmab/, U.S. /ˌtræˈstuzumæb/ Origin: Formed within English, by compounding. Etymons: English trastuz- , human adj., English monoclonal antibody. Etymology: < trastuz- (origin unknown) +-u- (in human adj.) + -mab , representing monoclonal antibody ( < monoclonal adj. + antibody n.). Pharmacology. A drug consisting of a preparation of humanized monoclonal antibodies directed against a cell surface receptor (human epidermal growth factor receptor 2; Her2) which contributes to the growth of some breast cancers, used in the treatment of such cancers.A proprietary name for this drug is Herceptin. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for cancer or leukemia amethopterin1948 Myleran1952 Laetrile1953 thioguanine1953 thioTEPA1953 mercaptopurine1954 methotrexate1955 busulfan1956 chlorambucil1956 cyclophosphamide1960 vinblastine1962 vincristine1962 levamisole1969 vinca alkaloid1970 doxorubicin1971 tamoxifen1972 Airol1974 trastuzumab1997 thiotepa- 1997 Business Wire (Nexis) 22 Dec. Genentech, based in South San Francisco, California, Friday announced favorable preliminary results from a Phase III trial of its trastuzumab (Herceptin) anti-HER2 monoclonal antibody in women with metastatic breast cancer who overexpress the HER2 oncogene. 1998 Lancet 10 Oct. 1205/1 On Sept. 25, the US FDA approved the first monoclonal antibody for breast cancer, Genentech's trastuzumab. 2008 Atlantic Monthly July 81/2 Breast-cancer patients with one of the two forms of the gene HER-2 responded differently to the new cancer drug trastuzumab (Herceptin). This is a new entry (OED Third Edition, November 2010; most recently modified version published online March 2022). < n.1997
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