transactivationn.
/ˌtrɑːnzaktɪˈveɪʃən//ˌtranzaktɪˈveɪʃən//ˌtrɑːnsaktɪˈveɪʃən//ˌtransaktɪˈveɪʃən/ Chiefly Biochemistry.
Activation of one entity by another which is trans to it; spec. in Biology, activation of a gene at one locus by the presence of a particular gene at another locus, esp. following infection by a virus.
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transactivation1965
1965 Jrnl. Amer. Chem. Soc. 87 659/1 This strong trans-activation undoubtedly plays an important role in the catalytic activity and facile ligand-exchange reactions observed for platinum metal-tin chloride complexes.
1970 Jrnl. Molecular Biol. 49 402 It is assumed that the N product is also involved in trans-activation of this segment in the presence of immunity.
1973 Molecular & Gen. Genetics 127 338 The efficiency of transactivation seems to vary considerably within different cells of one population.
1988 Nature 13 Oct. 606/2 The LTR also includes the TAR sequence which is located within the R region and functions as the target for tat transactivation.
This entry has not yet been fully updated (first published 1993; most recently modified version published online December 2020).
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n.1965