acetohexamiden.
/ˌasᵻtəʊˈhɛksəmʌɪd/, U.S. /əˌsidoʊˈhɛksəˌmaɪd/, /ˌæsəˌtoʊˈhɛksəˌmaɪd/ Pharmacology.
An oral hypoglycaemic drug of the sulphonylurea class.Chemical name: 1-[(p-acetylphenyl)-sulfonyl]-3-cyclohexylurea, C15H20N2O4S.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for diabetes
synthalin1927
protamine insulin1935
protamine zinc insulin1935
Ultralente1953
sulphonylurea1956
tolbutamide1956
phenformin1959
acetohexamide1961
metformin1961
tolazamide1963
1961 Proc. Soc. Exper. Biol. & Med. 107 584/2 Metabolism of acetohexamide 1-(p-acetylbenzenesulfonyl)-3-cyclohexylurea was investigated in dogs, rabbits, rats, and man.
1971 New Scientist 21 Jan. 136/2 The dispute in the United States over the safety and efficacy of the oral anti-diabetic agents of the sulphonylurea group, particularly tolbutamide, but potentially also tolazamide, acetohexamide and chloropropamide.
1989 Gastroenterology 96 1607 We report a case of cholestatic hepatitis accompanied by peripheral and hepatic eosinophilia in a patient taking acetohexamide for a period of 1.5 yr.
2002 Chem. Res. Toxicol. 15 240/2 The hypoglycemic agents tolbutamide, acetohexamide, and chlorpropamide do not exhibit antitumor activity.
This entry has been updated (OED Third Edition, September 2009; most recently modified version published online December 2021).
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n.1961