bisphosphonaten.
/bɪsˈfɒsfəneɪt/, U.S. /ˌbɪsˈfɑsfəˌneɪt/ An ester containing two phosphonate groups in the molecule; esp. any of a series of such compounds used to treat osteoporosis and other diseases that cause bone fragility.
ΚΠ
1961 Jrnl. Amer. Chem. Soc. 83 1734/2 Tetraethylmethylene bisphosphonate.., prepared from methylene iodide and triethyl phosphite, gave off hydrogen when added to a slurry of sodium hydride at room temperature.
1988 Update 15 Oct. 748/3 The bisphosphonates are potent inhibitors of bone resorption.
2003 Sci. Amer. Mar. 49/2 The most potent bisphosphonates—alendronate (Fosamax) and risedronate (Actonel)..can also increase bone density in most patients by 5 to 10 percent over three years.
2006 Chicago Tribune (Midwest ed.) 1 Oct. x. 30/1 Fosamax..acts, as all the bisphosphonates do, by slowing down the cells that destroy old bone.
This is a new entry (OED Third Edition, September 2018; most recently modified version published online December 2021).
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n.1961- to add oil to flame
- to add oil to the fire
- to add oil to the flame
- to add on
- to add one's name to the score-sheet
- to add one's name to the scoresheet
- to add or pair
- to add up
- to add up to
- to add value to
- to address the chair
- to address to a person under cover to
- to address to a person under cover to another
- to address to under cover to
- to address to under cover to another
- to address, bend, direct, dress, gye, etc one's style
- to adhere to a decision
- to adjust faith to
- to adjust the accounts
- to adjust the books
- to admiration
- to admit defeat
- to adopt measures
- to adopt the face of
- to advance by leaps and bounds