单词 | replicon |
释义 | repliconn. Genetics. A unit of genetic replication; spec. a nucleic acid molecule, or part of one, containing a single replication origin. ΘΚΠ the world > life > biology > biological processes > genetic activity > genetic components > [noun] > other genetic structures messenger1905 transforming principle1944 muton1957 prokaryon1957 recon1957 vector1958 operon1960 R1961 codon1962 replicon1963 regulon1964 promoter1965 promotor1966 transconjugant1974 cassette1977 1963 F. Jacob et al. in Cold Spring Harbor Symp. Quantitative Biol. 28 330/2 A genetic element such as an episome or a chromosome (of a bacterium or of a phage) constitutes a unit of replication or replicon. Such a unit can only replicate as a whole. 1976 Nature 29 Jan. 281/1 Each of these components is capable of autonomous replication in certain host strains of bacteria; that is, each is a ‘replicon’. 1997 Genomics 45 24 The human dystrophin gene..is organized into at least six replicons ranging in size from 170 to more than 500 kb. 2002 Internat. Jrnl. Cancer 98 554 Replicons based on alphaviruses are emerging as candidate vectors for vaccination and gene therapy purposes. This entry has been updated (OED Third Edition, December 2009; most recently modified version published online March 2022). < n.1963 |
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