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单词 replicon
释义

repliconn.

Brit. /ˈrɛplᵻkɒn/, U.S. /ˈrɛpləkɑn/
Origin: Formed within English, by derivation; modelled on a French lexical item. Etymons: replication n., -on suffix1.
Etymology: < replic- (in replication n.) + -on suffix1, after French réplicon (F. Jacob & S. Brenner 1963, in Comptes rendus hebd. de l'Acad. des Sci. 256 298).
Genetics.
A unit of genetic replication; spec. a nucleic acid molecule, or part of one, containing a single replication origin.
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the world > life > biology > biological processes > genetic activity > genetic components > [noun] > other genetic structures
messenger1905
transforming principle1944
muton1957
prokaryon1957
recon1957
vector1958
operon1960
R1961
codon1962
replicon1963
regulon1964
promoter1965
promotor1966
transconjugant1974
cassette1977
1963 F. Jacob et al. in Cold Spring Harbor Symp. Quantitative Biol. 28 330/2 A genetic element such as an episome or a chromosome (of a bacterium or of a phage) constitutes a unit of replication or replicon. Such a unit can only replicate as a whole.
1976 Nature 29 Jan. 281/1 Each of these components is capable of autonomous replication in certain host strains of bacteria; that is, each is a ‘replicon’.
1997 Genomics 45 24 The human dystrophin gene..is organized into at least six replicons ranging in size from 170 to more than 500 kb.
2002 Internat. Jrnl. Cancer 98 554 Replicons based on alphaviruses are emerging as candidate vectors for vaccination and gene therapy purposes.
This entry has been updated (OED Third Edition, December 2009; most recently modified version published online March 2022).
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n.1963
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