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pseudocholinesterase
pseudocholinesterase n. 
/ˌsudoʊˌkoʊlinˈɛstəˌreɪs/ Biochemistry an esterase which is less specific than acetylcholinesterase and present in blood and some other tissues, catalysing the hydrolysis of various choline esters and certain other compounds.
Brit. /ˌs(j)uːdə(ʊ)kəʊlɪnˈɛstəreɪz/
, /ˌs(j)uːdə(ʊ)kəʊlɪnˈɛstəreɪz/U.S. /ˌsudoʊˌkoʊlinˈɛstəˌreɪz/
, /ˌsudoʊˌkoʊlinˈɛstəˌreɪz//ˌsudoʊˌkoʊlinˈɛstəˌreɪs/ΚΠ
1943 B. Mendel & H. Rudney in Biochem. Jrnl. 37 59/1 There exist in the animal body two esterases capable of hydrolysing acetylcholine: a true cholinesterase acting exclusively on choline esters, and a non-specific enzyme, which hydrolyses not only esters of choline but a variety of non-choline esters as well... Experiments with both enzymes..have revealed a decisive difference between the two esterases, calling for a sharp distinction of the true cholinesterase from the non-specific enzyme, for which we venture to suggest the name pseudo-cholinesterase.
1984 M. J. Taussig Processes in Pathol. & Microbiol. (ed. 2) vii. 861 Other inherited enzyme defects which are revealed by drugs include pseudocholinesterase deficiency.
2005 Therapeutic Drug Monitoring 27 168 Thioridazine may prolong the serum half-life of cocaine by inhibiting the pseudocholinesterase-mediated catabolism of cocaine.
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as lemmas
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