单词 | nissl |
释义 | Nissln. Medicine. 1. Nissl method n. (also Nissl's method) the staining of neurons with Nissl's stain (see sense 4). ΘΚΠ the world > life > biology > laboratory analysis > processes > [noun] > using stains or dyes overstaining1880 Gram stain1884 Nissl method1895 osmication1899 counterstaining1901 cytophotometry1952 polychroming1958 immunofluorescence1960 1895 Science 8 Feb. 167/2 The formalin sections of the central nervous system may also be used for Rehm's modification of Nissl's method. 1899 Jrnl. Royal Microsc. Soc. 448 (heading) New Nissl method. 1901 Jrnl. Exper. Med. 5 551 The principles of Nissl's method are extremely simple. 1968 Brain 91 590 All the celloidin blocks were cut serially and at intervals of approximately ½ mm. Sections were stained by the Nissl method. 1997 Proc. National Acad. Sci. U.S.A. 94 14522/1 (caption) Brain morphology was analyzed on histological sections of embryos of different ages stained with cresyl violet (Nissl method). 2. Nissl body n. (also Nissl's body) any of various large basophilic granules containing ribosomes, found in the cell body of neurons. ΘΚΠ the world > life > biology > substance > cell > cell organelle or contents > [noun] > other organelles or contents raphide1831 body1839 raphid1863 mucigen1874 cell sap1875 globoid1875 raphis1879 pyrenoid1883 mucinogen1884 plastid1885 molluscum corpuscle1886 hyalosome1889 molluscum body1892 statolith1892 dictyosome1893 centrosome1895 Nissl body1898 Nissl granule1898 Nissl substance1899 archespore1901 blepharoplast1907 liposome1910 statocone1910 kinetosome1912 Golgi body1916 kinetoplast1925 lipochondrion1936 microsome1943 kappa1945 Pappenheimer body1947 microbody1954 lysosome1955 siderosome1957 ribosome1958 melanosome1961 cisterna1962 microtubule1962 plasmalemmasome1962 phagolysosome1963 informosome1964 monosome1964 mucocyst1965 peroxisome1965 rhoptry1967 spectrin1968 virosome1970 1898 Jrnl. Mental Sci. 44 730 The Nissl bodies..which stain deeply with basic dyes. 1904 Proc. Royal Soc. 73 384 The Nissl's bodies lost their affinity for basic dyes [during anaesthesia]. 1949 H. W. C. Vines Green's Man. Pathol. (ed. 17) xxxviii. 1068 (caption) A damaged nerve-cell in which the Nissl bodies are lost. 1986 A. S. Romer & T. S. Parsons Vertebr. Body (ed. 6) xvi. 539 Notable are clusters of darkly staining materials, Nissl bodies; these contain large amounts of RNA and numerous ribosomes. 3. Nissl granule n. (also Nissl's granule) = Nissl body n. at sense 2. ΘΚΠ the world > life > biology > substance > cell > cell organelle or contents > [noun] > other organelles or contents raphide1831 body1839 raphid1863 mucigen1874 cell sap1875 globoid1875 raphis1879 pyrenoid1883 mucinogen1884 plastid1885 molluscum corpuscle1886 hyalosome1889 molluscum body1892 statolith1892 dictyosome1893 centrosome1895 Nissl body1898 Nissl granule1898 Nissl substance1899 archespore1901 blepharoplast1907 liposome1910 statocone1910 kinetosome1912 Golgi body1916 kinetoplast1925 lipochondrion1936 microsome1943 kappa1945 Pappenheimer body1947 microbody1954 lysosome1955 siderosome1957 ribosome1958 melanosome1961 cisterna1962 microtubule1962 plasmalemmasome1962 phagolysosome1963 informosome1964 monosome1964 mucocyst1965 peroxisome1965 rhoptry1967 spectrin1968 virosome1970 1898 Proc. Royal Soc. 63 477 Mr. F. H. Scott..has found that Nissl's granules also give a distinct reaction for phosphorus. 1901 Jrnl. Exper. Med. 5 554 He finds the Nissl granules embedded in a homogeneous coagulum-like mass. 1953 A. G. E. Pearse Histochem. xiv. 318 The basophilia of Nissl's granules in nerve cells was entirely lost after this treatment. 1980 Proc. Royal Soc. B. 208 429 It has been suggested that these small cells with little cytoplasm and few Nissl granules may be astroglia. 4. Nissl stain n. (also Nissl's stain) a dye which normally stains the cell bodies of neurons, esp. methylene blue; (also) a microscopic specimen stained by Nissl's method. ΘΚΠ the world > life > biology > laboratory analysis > material > [noun] > staining material osmium tetroxide1869 picrocarmine1872 rose bengal1878 stain1880 erythrosin1884 Gram stain1884 vesuvin1885 Nile blue1888 pyronin1895 Janus green1898 counterstain1899 Nissl stain1899 Leishman stain1904 trypan blue1911 quinacrine mustard1957 1899 Philos. Trans. (Royal Soc.) B. 191 315 Cells of the pallium. Nissl Stain. Showing cell clusters. 1905 G. M. Gould Dict. New Med. Terms 129/1 Staining with Nissl's stain (methylene-blue). 1943 O. S. Strong & A. Elwyn Human Neuroanat. iii. 28/1 The significance of the Nissl stain..lies in the fact that..each type of nerve cell always presents the same appearance or ‘equivalent picture’ in normal conditions. 1990 Jrnl. Neuroendocrinol. 2 868/2 (caption) Fig. 2 is a Nissl stain of a hemisection through the medulla. 5. Nissl substance n. (also Nissl's substance) Nissl bodies collectively. ΘΚΠ the world > life > biology > substance > cell > cell organelle or contents > [noun] > other organelles or contents raphide1831 body1839 raphid1863 mucigen1874 cell sap1875 globoid1875 raphis1879 pyrenoid1883 mucinogen1884 plastid1885 molluscum corpuscle1886 hyalosome1889 molluscum body1892 statolith1892 dictyosome1893 centrosome1895 Nissl body1898 Nissl granule1898 Nissl substance1899 archespore1901 blepharoplast1907 liposome1910 statocone1910 kinetosome1912 Golgi body1916 kinetoplast1925 lipochondrion1936 microsome1943 kappa1945 Pappenheimer body1947 microbody1954 lysosome1955 siderosome1957 ribosome1958 melanosome1961 cisterna1962 microtubule1962 plasmalemmasome1962 phagolysosome1963 informosome1964 monosome1964 mucocyst1965 peroxisome1965 rhoptry1967 spectrin1968 virosome1970 1899 L. F. Barker Nerv. Syst. 110 He thinks it very wrong that these should be thrown all together and designated either ‘Nissl's substance’ or ‘tigroid substance’. 1933 Amer. Jrnl. Anat. 53 153 The cells are indeed very light; the Nissl substance is scanty. 1966 G. P. Wright & W. S. Symmers Systemic Pathol. II. xxxiv. 1147/1 In the cytoplasm of the neuron, certain polygonal, basiphile structures, known collectively as Nissl substance, are present. 1987 R. P. Saneto & J. de Vellis in A. J. Turner & H. S. Bachelard Neurochem. ii. 47 Neurones can be identified by polysomes containing regions (Nissl substance) and arrays of microtubules interspersed with neurofilaments. 6. Nissl degeneration n. (also Nissl's degeneration) degeneration of the cell body of a neuron after damage, accompanied by disintegration of the Nissl bodies. ΘΚΠ the world > life > biology > biological processes > cellular processes > [noun] > degeneration senescence1879 pyknosis1900 Nissl degeneration1911 the world > health and disease > ill health > a disease > disorders of internal organs > disorders of nervous system > [noun] > disorders of nerve cells neuronophagia1903 tigrolysis1903 neuronophagy1909 Nissl degeneration1911 1911 T. L. Stedman Pract. Med. Dict. 586/2 Nissl degeneration. 1949 H. W. C. Vines Green's Man. Pathol. (ed. 17) xxxviii. 1069 These cellular changes are called Nissl's degeneration. 1974 R. Passmore & J. S. Robson Compan. Med. Stud. III. ii. xxxiv. 33/2 The parent cell bodies undergo central chromatolysis (Nissl degeneration). This entry has been updated (OED Third Edition, December 2003; most recently modified version published online June 2022). < n.1895 |
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