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单词 niridazole
释义

niridazolen.

Brit. /nʌɪˈrɪdəzəʊl/, /nᵻˈrɪdəzəʊl/, U.S. /ˌnaɪˈrɪdəˌzoʊl/
Origin: Apparently formed within English, by compounding. Etymons: nitro- comb. form, imidazole n.
Etymology: Apparently < ni- (in nitro- comb. form) + -r- (perhaps an arbitrary element) + -idazole (in imidazole n.), representing components of the molecular structure.
Pharmacology.
An anthelmintic drug which has been used in the treatment of schistosomiasis (bilharzia) and is usually given orally; 1-(5-nitrothiazol-2-yl) imidazolidin-2-one, C6H6N4O3S.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > remedies for parasitic infections > [noun] > vermifuge or anthelminthic > others
brayera1875
piperazine1889
piperazidine1891
hexylresorcinol1924
thiabendazole1961
niridazole1966
tetramisole1966
mebendazole1971
oxamniquine1972
albendazole1976
1966 Brit. Med. Jrnl. 19 Nov. 1261/2 A male child aged 17 months..recently died in the Mwanza General Hospital following Ambilhar (niridazole) therapy.
1978 Nature 22 June 628/1 The development of niridazole has provided an important new therapy for schistosomiasis due to Schistosoma haematobium.
1993 Teratology 47 209 Niridazole does not produce DNA damage but appears to induce asymmetric malformations by depleting embryonic oxygen.
This entry has been updated (OED Third Edition, December 2003; most recently modified version published online March 2022).
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n.1966
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