neurophysinn.
/ˌnjʊərə(ʊ)ˈfʌɪsɪn/, U.S. /ˌn(j)ʊroʊˈfaɪsɪn/ Biochemistry and Physiology.
Any of a family of proteins that act as carriers for the neurohypophysial peptide hormones oxytocin and vasopressin.
ΘΚΠ
the world > life > biology > biological processes > action of nervous system > [noun] > reception or transmission of impulses > transmitters
rectifier1895
transmitter1930
sympathin1931
noradrenaline1932
neurohumour1933
substance P1934
norepinephrine1937
neurohormone1939
neurosecretion1956
neurophysin1958
vasoactive intestinal (poly)peptide1958
neurotransmitter1961
VIP1972
neuropeptide1973
1958 Science 13 June 1396/3 According to Acher (France), the neurosecretory material consists of an ‘inactive’. large protein molecule (neurophysine) and several polypeptides with hormonal activities.
1968 Proc. Royal Soc. B. 170 4 All subsequent investigators..isolated a protein or its hormone-free derivative, called ‘neurophysine’.
1970 Biochem. Jrnl. 116 908/2 The neurophysins of the pig form a group of proteins of different electrophoretic mobilities but all possessing the capacity to bind oxytocin and [8-lysine]-vasopressin.
1981 R. N. Hardy Endocrine Physiol. vi. 57 The hormone, together with its neurophysin, is released from the nerve ending in response to nerve impulses travelling down the axons.
1990 Chem. Senses 15 200 Many non-covalently bound ligands, such as the heme ligands of the globins or the peptides associated with the neurophysins, cannot be separated from the binding protein by dialysis or gel filtration.
This entry has been updated (OED Third Edition, September 2003; most recently modified version published online March 2022).
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n.1958