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单词 myxoedema
释义

myxoedemamyxedeman.

Brit. /ˌmɪksᵻˈdiːmə/, U.S. /ˌmɪksəˈdimə/
Forms: 1800s– myxedema, 1800s– myxoedema.
Origin: Formed within English, by compounding. Etymons: myxo- comb. form, oedema n.
Etymology: < myxo- comb. form + oedema n. (see quot. 1878). Compare French myxoedème (1879; < English).
Medicine.
Originally: the clinical syndrome caused by hypothyroidism, the symptoms of which include mental slowness, muscle weakness, reduced body temperature, hair loss, and a firm oedematous thickening of the skin. Later: spec. the cutaneous manifestations of this syndrome, caused by mucopolysaccharide deposition in the subcutaneous tissue and dermis (sometimes seen also, esp. in the pretibial area, in Graves' disease).
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the world > health and disease > ill health > a disease > disorders of internal organs > glandular disorders > [noun] > other thyroid gland disorders
myxoedema1878
thyroiditis1889
Riedel1912
struma lymphomatosa1931
1878 W. M. Ord in Medico-chirurg. Trans. 61 71 I propose to give the name of Myxoedema to the affection.
1897 T. C. Allbutt et al. Syst. Med. III. 319 The effects of myxœdema..can be removed by the administration of thyroid extract.
1947 Commerc. Salmon-fisheries Brit. Columbia (Dept. Fisheries, Brit. Columbia) (rev. ed.) 54 The pigs feeding in and around the village rarely suffer from myxedema or other diseases of the thyroid.
1990 Here's Health Dec. 76/1 Then a private physician diagnosed myxoedema and put me on Thyroxine, and in two months I lost 34 pounds and began to feel better.
2001 European Jrnl. Endocrinol. 146 35 Pretibial myxedema (PTM), mainly characterized by the accumulation of glycosaminoglycans in the dermis and subcutaneous tissue, is an extrathyroidal manifestation of autoimmune Graves' disease.
This entry has been updated (OED Third Edition, June 2003; most recently modified version published online March 2022).
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n.1878
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