multivalencyn.

Brit.

/ˌmʌltɪˈveɪlənsi/,

/ˌmʌltɪˈveɪln̩si/, U.S.

/ˌməltiˈveɪl(ə)nsi/,

/ˌməlˌtaɪˈveɪl(ə)nsi/,

/ˌməltəˈveɪl(ə)nsi/

Origin: Formed within English, by compounding. Etymons: multi- comb. form, -valency comb. form.

Etymology: < multi- comb. form + -valency comb. form. Compare slightly earlier multivalence n., multivalent adj.

Science.

The property, esp. (Immunology) of an antibody or antigen or (Chemistry) of an atom or molecule, of being multivalent; = multivalence n. 1, polyvalence n.

ΘΚΠ

the world > matter > chemistry > valency > [noun] > multivalency

multivalencya1881

sexivalent1931

a1881 A. Barratt Physical Metempiric (1883) 64 Multi-valency of atoms.

1906 Jrnl. Chem. Soc. 89 ii. 1738 There are..limitations to the extent to which different elements exhibit multivalency; thus, carbon seems always to be quadrivalent, but sulphur and nitrogen show changeable valency.

1963 J. H. Humphrey & R. G. White Immunol. for Students of Med. vi. 218 The so-called ‘sandwich’ technique for the detection of antibody..employs a primary layer of a dilute solution of unlabelled antigen... Such a method depends upon the multivalency of the antigen.

1988 Nature 25 Aug. 720/2 If each [protein] subunit has two binding sites, the association..into trimers should not be required..; the bivalency (or multivalency) in single subunits may be sufficient to induce bundling.

1997 Immunotechnology 3 83 We summarize recent progress in engineering multivalency from recombinant antibody fragments by using..chemically crosslinked antibody fragments.

This entry has been updated (OED Third Edition, March 2003; most recently modified version published online March 2022).

单词	multivalency
释义	multivalencyn. Brit. /ˌmʌltɪˈveɪlənsi/, /ˌmʌltɪˈveɪln̩si/, U.S. /ˌməltiˈveɪl(ə)nsi/, /ˌməlˌtaɪˈveɪl(ə)nsi/, /ˌməltəˈveɪl(ə)nsi/ Origin: Formed within English, by compounding. Etymons: multi- comb. form, -valency comb. form. Etymology: < multi- comb. form + -valency comb. form. Compare slightly earlier multivalence n., multivalent adj. Science. The property, esp. (Immunology) of an antibody or antigen or (Chemistry) of an atom or molecule, of being multivalent; = multivalence n. 1, polyvalence n. ΘΚΠ the world > matter > chemistry > valency > [noun] > multivalency multivalencya1881 sexivalent1931 a1881 A. Barratt Physical Metempiric (1883) 64 Multi-valency of atoms. 1906 Jrnl. Chem. Soc. 89 ii. 1738 There are..limitations to the extent to which different elements exhibit multivalency; thus, carbon seems always to be quadrivalent, but sulphur and nitrogen show changeable valency. 1963 J. H. Humphrey & R. G. White Immunol. for Students of Med. vi. 218 The so-called ‘sandwich’ technique for the detection of antibody..employs a primary layer of a dilute solution of unlabelled antigen... Such a method depends upon the multivalency of the antigen. 1988 Nature 25 Aug. 720/2 If each [protein] subunit has two binding sites, the association..into trimers should not be required..; the bivalency (or multivalency) in single subunits may be sufficient to induce bundling. 1997 Immunotechnology 3 83 We summarize recent progress in engineering multivalency from recombinant antibody fragments by using..chemically crosslinked antibody fragments. This entry has been updated (OED Third Edition, March 2003; most recently modified version published online March 2022). < n.a1881
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