monosomyn.

Brit.

/ˈmɒnə(ʊ)ˌsəʊmi/, U.S.

/ˈmɑnəˌsoʊmi/

Origin: Formed within English, by derivation. Etymons: monosome n., -y suffix³.

Etymology: < monosome n. + -y suffix³. Compare earlier monosomic adj., polysomy n.

Genetics.

The condition of being monosomic; the absence of one of a pair of homologous chromosomes; an instance of this.

ΘΚΠ

the world > life > biology > biological processes > genetic activity > genetic components > [noun] > chromosome > types of chromosome > condition

trisomy1930

monosomy1931

polyteny1942

tetrasomy1961

nullisomy1966

1931 Amer. Naturalist 65 243 Subdivisions of this class are:..(b) Combinations, i.e., addition or subtraction of entire individual chromosomes (trisomy, polysomy, monosomy, etc.).

1948 Nature 5 June 873/1 Genetical experience shows that, like polyploidy, monosomy and polysomy in a wide range of plants and animals can characterize whole individuals.

1961 Lancet 16 Sept. 625/1 Both cases show monosomy and trisomy involving the X chromosome or an autosome of similar size and morphology.

1967 Proc. National Acad. Sci. U.S.A. 57 1676 Such measurements..allow quantitative comparison of the behavior of normal cells with those possessing specific chromosomal monosomies, polysomies, deletions, and other aberrations.

1972 Science 5 May 518/3 Not so well documented..are the occasional observations of monosomy, trisomy and other aneuploidies.

1987 C. A. Clarke Human Genetics & Med. (ed. 3) viii. 61 Monosomy as regards the autosomes is usually, if not always, lethal.

2000 Amer. Jrnl. Human Genetics 67 515 Monosomy for the X chromosome in humans creates a genetic Achilles' heel for nature to deal with.

This entry has been updated (OED Third Edition, December 2002; most recently modified version published online March 2022).

单词	monosomy
释义	monosomyn. Brit. /ˈmɒnə(ʊ)ˌsəʊmi/, U.S. /ˈmɑnəˌsoʊmi/ Origin: Formed within English, by derivation. Etymons: monosome n., -y suffix³. Etymology: < monosome n. + -y suffix³. Compare earlier monosomic adj., polysomy n. Genetics. The condition of being monosomic; the absence of one of a pair of homologous chromosomes; an instance of this. ΘΚΠ the world > life > biology > biological processes > genetic activity > genetic components > [noun] > chromosome > types of chromosome > condition trisomy1930 monosomy1931 polyteny1942 tetrasomy1961 nullisomy1966 1931 Amer. Naturalist 65 243 Subdivisions of this class are:..(b) Combinations, i.e., addition or subtraction of entire individual chromosomes (trisomy, polysomy, monosomy, etc.). 1948 Nature 5 June 873/1 Genetical experience shows that, like polyploidy, monosomy and polysomy in a wide range of plants and animals can characterize whole individuals. 1961 Lancet 16 Sept. 625/1 Both cases show monosomy and trisomy involving the X chromosome or an autosome of similar size and morphology. 1967 Proc. National Acad. Sci. U.S.A. 57 1676 Such measurements..allow quantitative comparison of the behavior of normal cells with those possessing specific chromosomal monosomies, polysomies, deletions, and other aberrations. 1972 Science 5 May 518/3 Not so well documented..are the occasional observations of monosomy, trisomy and other aneuploidies. 1987 C. A. Clarke Human Genetics & Med. (ed. 3) viii. 61 Monosomy as regards the autosomes is usually, if not always, lethal. 2000 Amer. Jrnl. Human Genetics 67 515 Monosomy for the X chromosome in humans creates a genetic Achilles' heel for nature to deal with. This entry has been updated (OED Third Edition, December 2002; most recently modified version published online March 2022). < n.1931
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