mitogenicadj.
/ˌmʌɪtə(ʊ)ˈdʒɛnɪk/, U.S. /ˌmaɪdəˈdʒɛnɪk/ Cell Biology and Immunology.
Inducing or stimulating mitosis, mitogenetic; (later) (Immunology) inducing lymphocyte transformation. Also: of or relating to this activity.
ΘΚΠ
the world > life > biology > biological processes > genetic activity > [adjective] > mitosis > promoting
mitogenetic1925
mitogenic1929
1929 Bot. Gaz. 87 438 The so-called ‘mitogenic ray’ theory of Gurwitsch.
1946 Philos. Trans. (Royal Soc.) B. 231 511 The naturally occurring mitogenic hormones may all be steroids.
1962 Hereditas 48 619 (heading) On the effect of mitogenic plant extracts (phyto-hemagglutinin) on human white blood cells cultivated in vitro.
1970 Nature 26 Sept. 1351/1 When certain mitogenic agents are added to lymphocytes cultured in serum, the cells are activated to transform and divide.
1984 Science 22 June 1346/2 Calmodulin is selectively increased..on release of growth-arrested cells in response to a mitogenic stimulus.
Derivatives
mitoˈgenically adv. by, by means of, or with respect to a mitogen or mitogenic activity.
ΚΠ
1970 Biochimica et Biophysica Acta 222 565 (title) Changes in the carbohydrate metabolism of mitogenically stimulated human peripheral lymphocytes.
1990 EMBO Jrnl. 9 2419/2 Although it remained ligand-responsive, the ΔKI mutant was mitogenically impaired.
2001 Philos. Trans. (Royal Soc.) B. 356 83 Germinal centre B cells represent a stage of differentiation that can be defined by a gene expression signature that is not shared by other highly proliferative B-cell populations such as mitogenically activated peripheral blood B cells.
This entry has been updated (OED Third Edition, June 2002; most recently modified version published online March 2022).
<
adj.1929