Metopironen.

Brit.

/ˌmɛtə(ʊ)ˈpɪrəʊn/, U.S.

/ˌmɛdəˈpɪrˌoʊn/

Forms: also with lower-case initial.

Origin: Perhaps formed within English, by derivation. Etymons: methyl n., -o- connective, English pyrid , -one suffix.

Etymology: Perhaps < met- (in methyl n.) + -o- connective + pir- (in pyrid, with alteration of y to i ) + -one suffix, after the chemical name 2-methyl-1,2-di(pyrid-3-yl)propan-1-one (see metyrapone n.).

Pharmacology.

The drug metyrapone.A proprietary name in the United States.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > [noun] > drugs used as testing agents

tuberculin1891

lepromin1929

penatin1942

sulphobromophthalein1945

toxoplasmin1948

Metopirone1960

metyrapone1962

leprolin1971

1960 Lancet 17 Dec. 1332/2 Metopirone is an 11 β-hydroxylase inhibitor which presumably prevents the production of aldosterone by the adrenal gland.

1962 Lancet 19 May 1041/2 The duration of the action of metopirone was investigated, in order to determine the best dosage schedule in tests of pituitary function.

1973 Arch. Internat. de Pharmacodynamie et de Thérapie 202 93 Metopirone was found to provoke in normal, but not in adrenalectomized rats, a three-fold increase in blood sugar and a four-fold increase in plasma adrenaline.

1993 Internat. Arch. Allergy & Immunol. 101 215 We performed antigen challenge in dogs treated with Metopirone.

This entry has been updated (OED Third Edition, December 2001; most recently modified version published online March 2022).

单词	metopirone
释义	Metopironen. Brit. /ˌmɛtə(ʊ)ˈpɪrəʊn/, U.S. /ˌmɛdəˈpɪrˌoʊn/ Forms: also with lower-case initial. Origin: Perhaps formed within English, by derivation. Etymons: methyl n., -o- connective, English pyrid , -one suffix. Etymology: Perhaps < met- (in methyl n.) + -o- connective + pir- (in pyrid, with alteration of y to i ) + -one suffix, after the chemical name 2-methyl-1,2-di(pyrid-3-yl)propan-1-one (see metyrapone n.). Pharmacology. The drug metyrapone.A proprietary name in the United States. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > [noun] > drugs used as testing agents tuberculin1891 lepromin1929 penatin1942 sulphobromophthalein1945 toxoplasmin1948 Metopirone1960 metyrapone1962 leprolin1971 1960 Lancet 17 Dec. 1332/2 Metopirone is an 11 β-hydroxylase inhibitor which presumably prevents the production of aldosterone by the adrenal gland. 1962 Lancet 19 May 1041/2 The duration of the action of metopirone was investigated, in order to determine the best dosage schedule in tests of pituitary function. 1973 Arch. Internat. de Pharmacodynamie et de Thérapie 202 93 Metopirone was found to provoke in normal, but not in adrenalectomized rats, a three-fold increase in blood sugar and a four-fold increase in plasma adrenaline. 1993 Internat. Arch. Allergy & Immunol. 101 215 We performed antigen challenge in dogs treated with Metopirone. This entry has been updated (OED Third Edition, December 2001; most recently modified version published online March 2022). < n.1960
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