metrifonaten.

Brit.

/mᵻˈtrɪfəneɪt/, U.S.

/məˈtrɪfəˌneɪt/

Forms: 1900s– metrifonate, 1900s– metriphonate.

Origin: Formed within English, by compounding. Etymons: methyl n., trichloro- comb. form, phosphonate n.

Etymology: < me- (in methyl n.) + tri- (in trichloro- comb. form) + -fonate (respelling, with change of ph to f, of -phonate in phosphonate n.).

Agriculture and Pharmacology.

A chlorinated organophosphate compound that is a cholinesterase inhibitor, used as an agricultural insecticide, in the medical and veterinary treatment of various parasitic (especially helminthic) infections, and in the experimental treatment of certain forms of dementia; dimethyl (2,2,2-trichloro-1-hydroxyethyl) phosphonate, C₄H₈Cl₃O₄P. Also called trichlorfon.

ΚΠ

1965 Brit. Vet. Codex 1965 239 Metriphonate is an organophosphorus compound effective both as an insecticide and as an anthelmintic.

1977 Martindale's Extra Pharmacopoeia (ed. 27) 793/1 Metriphonate has..been used in the treatment of human helminth infestations, especially those due to Schistosoma haematobium.

1998 Daily Tel. 21 May 11/3 Moderately to mildly demented patients who took the drug, metrifonate, were less likely to have hallucinations or be apathetic, depressed and agitated.

2000 Jrnl. Geriatric Psychiatry & Neurol. 13 9 The objective of this analysis was to evaluate comprehensively the efficacy of metrifonate, a long-acting acetylcholinesterase inhibitor, in improving the ability of mild-to-moderate Alzheimer's disease patients to perform activities of daily living.

This is a new entry (OED Third Edition, December 2001; most recently modified version published online March 2022).

单词	metrifonate
释义	metrifonaten. Brit. /mᵻˈtrɪfəneɪt/, U.S. /məˈtrɪfəˌneɪt/ Forms: 1900s– metrifonate, 1900s– metriphonate. Origin: Formed within English, by compounding. Etymons: methyl n., trichloro- comb. form, phosphonate n. Etymology: < me- (in methyl n.) + tri- (in trichloro- comb. form) + -fonate (respelling, with change of ph to f, of -phonate in phosphonate n.). Agriculture and Pharmacology. A chlorinated organophosphate compound that is a cholinesterase inhibitor, used as an agricultural insecticide, in the medical and veterinary treatment of various parasitic (especially helminthic) infections, and in the experimental treatment of certain forms of dementia; dimethyl (2,2,2-trichloro-1-hydroxyethyl) phosphonate, C₄H₈Cl₃O₄P. Also called trichlorfon. ΚΠ 1965 Brit. Vet. Codex 1965 239 Metriphonate is an organophosphorus compound effective both as an insecticide and as an anthelmintic. 1977 Martindale's Extra Pharmacopoeia (ed. 27) 793/1 Metriphonate has..been used in the treatment of human helminth infestations, especially those due to Schistosoma haematobium. 1998 Daily Tel. 21 May 11/3 Moderately to mildly demented patients who took the drug, metrifonate, were less likely to have hallucinations or be apathetic, depressed and agitated. 2000 Jrnl. Geriatric Psychiatry & Neurol. 13 9 The objective of this analysis was to evaluate comprehensively the efficacy of metrifonate, a long-acting acetylcholinesterase inhibitor, in improving the ability of mild-to-moderate Alzheimer's disease patients to perform activities of daily living. This is a new entry (OED Third Edition, December 2001; most recently modified version published online March 2022). < n.1965
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