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单词 ketosis
释义

ketosisn.

Brit. /kiːˈtəʊsɪs/, /kɪˈtəʊsɪs/, U.S. /kiˈtoʊsəs/
Etymology: < ket- (in keto- comb. form) + -osis suffix.
Medicine.
A condition characterized by an increased production of ketone bodies, which is associated with a predominance of fat metabolism and with diabetes.
ΘΚΠ
the world > health and disease > ill health > a disease > disorders of internal organs > metabolic disorders > [noun] > other metabolic disorders
xanthomatosis1900
Tay-Sachs1907
ketosis1917
protein shock1917
hyperinsulinism1924
Niemann–Pick1928
tyrosinosis1932
von Gierke's disease1933
phenylketonuria1935
cystic fibrosis1938
mucoviscidosis1945
cystinosis1949
oxalosis1952
McArdle1957
orotic aciduria1959
PKU1961
sphingolipidosis1962
Reye's syndrome1965
Menkes1969
1917 F. M. Allen in Amer. Jrnl. Med. Sci. CLIII. 335 No other name but acidosis exists for the metabolic process which it denotes. Ketonuria and ketonemia have their accurate place but do not cover the ground. Possibly the word ketosis might be suggested and used for special purposes, but the change of established usage would be difficult and seems unnecessary.
1925 Biochem. Jrnl. 19 948 In man after a relatively short period of starvation..a considerable ketosis appears.
1951 A. Grollman Pharmacol. & Therapeutics vii. 151 The paroxysmal cerebral dysrhythmia characteristic of epilepsy may be altered by inducing ketosis by a low carbohydrate, high fat diet.
1960 Farmer & Stockbreeder 22 Mar. 136/1 There does appear to be a connection between the heavy feeding of kale, and the incidence of ketosis (acetonæmia), but in rather a roundabout way.
1961 A. S. MacNalty Brit. Med. Dict. 12/2 Acetone bodies, aliphatic ketones and hydroxy ketones found in the blood and urine of severe diabetics as the result of the incomplete breakdown of fatty and amino acids, a condition known as ketosis.
1970 R. W. McGilvery Biochemistry xxii. 530 However, the meat-fat diet does cause the appearance of an asymptomatic ketosis.

Derivatives

keˈtotic adj. suffering from or associated with ketosis.
ΘΚΠ
the world > health and disease > ill health > a disease > disorders of internal organs > metabolic disorders > [adjective] > other metabolic disorders
von Gierke1933
ketotic1943
cystinotic1961
orotic aciduric1961
phenylketonuric1961
1943 Jrnl. Amer. Med. Assoc. 2 Jan. 52/2 During episodes of ketotic acidosis it was necessary to give 2,360, 2,500 and 2,795 units of insulin in twenty-four hours before adequate control was accomplished.
1959 Jrnl. Appl. Physiol. 14 1028/1 The turnover time was increased also by about 1/ 5 in the ketotic cows.
1961 L. C. Martin Clin. Endocrinol. (ed. 3) ii. 52 Uncontrolled diabetics with high blood sugar levels do not as a rule suffer from anorexia unless they are also ketotic.
1972 Jrnl. Clin. Investig. 51 1440/1 The cause of ketotic hypoglycemia, the commonest form of hypoglycemia in childhood, is not known.
This entry has not yet been fully updated (first published 1976; most recently modified version published online March 2022).
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