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单词 isophane
释义

isophaneisophenen.

/ˈʌɪsə(ʊ)feɪn/ /ˈaɪsə(ʊ)fiːn/
Etymology: formed as isophane adj.; compare phen- comb. form, pheno- comb. form.
A line (imaginary or on a map) linking places in which seasonal biological phenomena (the flowering of plants, etc.) occur at the same time.
ΘΚΠ
the world > the earth > earth sciences > geography > map-making > map > [noun] > line on map > biological phenomena
isophane1918
isepiptesis1926
isochar1963
1918 A. D. Hopkins in Monthly Weather Rev. (U.S.) Suppl. No. 9. 9/1 Taking base maps of North America and of the major and minor political divisions, parallel lines (designated as isophanes) are drawn on them to define, according to the bioclimatic law, theoretical lines and zones of equal phenomena as to time of occurrence and equal bioclimatic conditions, at the same level.
1929 V. E. Shelford Lab. & Field Ecol. i. 15 An isophenal map was prepared with isophenes drawn through equal-event dates at the same altitude.
1931 Trans. Entomol. Soc. Lond. 79 183 Local conditions..cause considerable departures in the actual dates of seasonal events from those indicated by isophanes.
1947 R. F. Daubenmire Plants & Environment iv. 219 From phenologic data maps can be drawn with lines (isophenes) connecting locations where plants are in the same stage of development at the same time.
1963 E. Mayr Animal Species & Evol. xiii. 362 This north-south cline is crossed by the isophenes, lines connecting all populations with the same phenotype.

Derivatives

isoˈphanal adj.
ΚΠ
1931 Trans. Entomol. Soc. Lond. 79 183 Instead of basing the isophanal map on degrees of latitude and longitude, he [sc. Znamenskiǐ] made use of the mean annual isotherms.
isoˈphenal adj.
ΘΚΠ
the world > the earth > earth sciences > geography > map-making > map > [adjective] > line on map > biological phenomena
isophenal1918
1918 A. D. Hopkins in Monthly Weather Rev. (U.S.) Suppl. No. 9. 8 (caption) Isophenal map of North America.
This entry has not yet been fully updated (first published 1976; most recently modified version published online March 2020).

isophaneadj.

/ˈʌɪsəʊfeɪn/
Etymology: < iso- comb. form + Greek -ϕανης showing, appearing ( < ϕαίνειν to show, cause to appear).
Pharmacology.
a. Designating that ratio of protamine to insulin which, in a solution made by mixing solutions of the individual substances, gives rise to equal turbidity in two equal samples taken after a precipitate has been allowed to form when one sample has sufficient insulin added to it to precipitate all the protamine in it and the other a sufficient amount of protamine to precipitate all the insulin.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medical preparations of specific origin > hormones and substances with same effect > [adjective] > ratio of protamine to insulin
isophane1946
1946 Krayenbühl & Rosenberg in Rep. Steno Memorial Hosp. I. 65 The proportion of protamine to insulin must be nearly isophane. At isophane proportions the formation of crystals is rapid.
1950 Federal Register (U.S.) 2 Nov. 7363/2 The isophane ratio shall be expressed as milligrams of protamine per 100 U.S.P. Units of insulin.
1955 Dispensatory U.S.A. (ed. 25) 686/2 The most useful of these mixtures, for many patients, proved to be the 2:1 mixture of regular insulin and protamine zinc insulin. In this mixture protamine is present to the extent of about 0·5 mg. per 100 units of insulin, which is the combining proportion, or so-called isophane ratio, of protamine and insulin.
b. Applied to a crystalline mixture of insulin and protamine in the isophane ratio with zinc, which has longer-lasting effects than pure insulin. Also elliptical as n.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medical preparations of specific origin > hormones and substances with same effect > [noun]
epinephrine1899
pituitrin1909
oxytocin1927
Pitocin1929
Pitressin1929
progestin1930
progesterone1935
methyltestosterone1936
pregnenolone1936
hexœstrol1939
stilboestrol1939
hydroxyprogesterone1941
progestogen1941
Premarin1942
hydroxycorticosterone1943
gestagen1948
hydrocortisone1951
cortisol1953
fluorohydrocortisone1954
isophane1954
prednisolone1955
prednisone1955
norethisterone1956
norethynodrel1957
dexamethasone1958
fludrocortisone1958
norethindrone1960
antidiuretic hormone1961
medroxyprogesterone1962
Pergonal1963
mesterolone1965
norgestrel1966
quinestrol1966
pancuronium1967
pentagastrin1967
levonorgestrel1977
1954 A. Grollman Pharmacol. & Therapeutics (ed. 2) xxvi. 606 (table) NPH Insulin (Isophane).
1955 Dispensatory U.S.A. (ed. 25) 686/2 In preparing Isophane Insulin Injection, sufficient insulin is used to provide either 40 or 80 U.S.P. Insulin Units for each ml. of the Injection.
1955 Brit. Med. Jrnl. 19 Feb. 478/2 Having used isophane..since November, 1953, and in more than 60 diabetics, I find it easily the most satisfactory one-shot-a-day insulin available.
1966 Lancet 24 Dec. 1389/2 A 20-year-old diabetic patient, who was poorly controlled on 45 units isophane insulin in the morning and 35 units isophane insulin in the evening, was admitted in diabetic ketoacidosis.
1968 Pond & Oakley in W. G. Oakley et al. Clin. Diabetes xxiii. 602 A comparable method of control by a single morning injection is the use of a mixture of isophane (NPH) and SI.
This entry has not yet been fully updated (first published 1976; most recently modified version published online March 2019).
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n.1918adj.1946
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