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单词 hepadnavirus
释义

hepadnavirusn.

Brit. /hɛˈpadnəˌvʌɪrəs/, U.S. /hɛˈpædnəˌvaɪrəs/
Origin: Formed within English, by compounding. Etymons: hepatitis n., DNA n., virus n.
Etymology: < hepa- (in hepatitis n.) + DNA n. (here treated as though an acronym rather than an initialism) + virus n.
Virology.
Any member of the genus Hepadnavirus or family Hepadnaviridae of enveloped, partially double-stranded DNA viruses which are pathogens of a wide range of mammals and birds, infecting the liver and causing hepatitis (hepatitis B in humans) and (in some cases) hepatocellular carcinoma. Also (in form Hepadnavirus): the genus itself.Hepadnaviruses persistently infect liver cells in the form of covalently closed circular DNA (cccDNA). Their replication involves a viral DNA polymerase with a reverse transcriptase function, which is a target for antiviral therapy.
ΚΠ
1982 Jrnl. Virol. 42 135 The hepatitis B-like viruses (human hepatitis B virus, woodchuck hepatitis virus, ground squirrel hepatitis virus, and duck hepatitis B virus) are hepatotropic DNA viruses which have been referred to collectively as ‘hepadnaviruses’.
1991 Sci. Amer. Apr. 51/2 Some understanding of HBV [= Hepatitis B virus] has come from studies of similar viruses, called hepadnaviruses, that cause hepatitislike conditions in animals.
2006 Jrnl. Hepatol. 44 S10/1 HBV is a member of the Hepadnaviridae family, genus Hepadnavirus.
This is a new entry (OED Third Edition, June 2008; most recently modified version published online March 2022).
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n.1982
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