deoxycorticosteronen.
Biochemistry.
A steroid compound, C21H30O3, occurring in the adrenal cortex and also prepared synthetically.
ΚΠ
1937 Steiger & Reichstein in Nature 29 May 926/1 This compound differs from corticosterone only by the absence of the fourth oxygen, and can therefore also be called desox-corticosterone.
1938 Chem. Abstr. 32 578 The structure of the biol. active desoxycorticosterone from stigmasterol.
1941 Ann. Reg. 1940 344 Deoxycorticosterone was prepared artifically.
1952 G. H. Bourne Cytol. & Cell Physiol. (ed. 2) xi. 478 From the adrenal cortex there have been extracted two main groups of physiologically active steroids. One group, exemplified by desoxycorticosterone, acts primarily on the salt balance of the body and regulates the excretion of Na and Cl by the kidney.
1956 Nature 28 Jan. 189/2 Comparisons are being made of the wool growth of adrenalectomized sheep maintained on different levels of cortisone and deoxycorticosterone.
1965 New Scientist 1 July 33/1 The true mineralocorticoid hormone is aldosterone, but there are compounds such as deoxycorticosterone and fluorocortisol that have potent related properties.
This entry has not yet been fully updated (first published 1972; most recently modified version published online December 2020).
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n.1937