anthracyclinen.
/ˌanθrəˈsʌɪkliːn/, /ˌanθrəˈsʌɪklɪn/, U.S. /ˌænθrəˈsaɪˌklin/ Pharmacology.
Any of a class of antineoplastic drugs whose molecules contain a tetracyclic nucleus related to anthraquinone and whose major action is to inhibit the uncoiling and coiling of DNA necessary for its transcription and replication. Frequently attributive.Examples of this class of drug include daunorubicin, doxorubicin.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > antibiotics > [noun] > other antibiotics
pyocyanase1900
fumigatin1938
M and B1938
gramicidin1940
tyrocidine1940
tyrothricin1940
clavacin1942
fumigacin1942
streptothricin1942
aspergillic acid1943
aspergillin1943
clavatin1943
helvolic acid1943
streptomycin1944
subtilin1944
bacitracin1945
viridin1945
javanicin1946
nisin1947
nitrofurazone1947
polymyxin1947
aureomycin1948
chloramphenicol1949
clitocybin1949
neomycin1949
Terramycin1950
viomycin1950
cephalosporin1951
fumagillin1951
nigericin1951
achromycin1952
carbomycin1952
erythromycin1952
nystatin1952
oxytetracycline1952
tetracycline1952
chlortetracycline1953
nitrofurantoin1953
oligomycin1953
puromycin1953
bacteriocin1954
albomycin1955
spiramycin1955
valinomycin1955
amphotericin B1956
mitomycin1956
novobiocin1956
oleandomycin1956
paromomycin1956
vancomycin1956
kanamycin1957
macrolide1957
ristocetin1957
streptovaricin1957
ethionamide1959
rifamycin1959
strep1959
mithramycin1960
fucidin1961
virginiamycin1961
cephalothin1962
fusidic acid1962
nonactin1962
trimethoprim1962
daunomycin1963
lincomycin1963
anthracycline1964
cephaloridine1964
spectinomycin1964
doxycycline1966
rifampicin1966
minocycline1967
rifampin1968
Adriamycin1969
daunorubicin1969
ribostamycin1970
doxorubicin1971
tobramycin1971
milbemycin1975
fluoroquinolone1984
1964 L. Mitscher et al. in Jrnl. Pharmaceut. Sci. 53 1139 (heading) Ruticulomycins, new anthracycline antibiotics.
1978 Brit. Med. Jrnl. 28 Jan. 199/2 Mathe et al. added an anthracycline to vincristine and prednisolone and achieved 100% complete remission in small series of such high-risk patients.
1998 L. Margulis & K. V. Schwartz Five Kingdoms (ed. 3) iv. 352 Bleomycins and anthracyclines, isolated from Streptomyces verticillus..interfere with DNA replication.
2008 Sun (Nexis) 13 Dec. 24 Only tumours with a duplication of chromosome 17 benefited from anthracyclines—which can boost survival rates by a third but have serious side-effects.
This entry has been updated (OED Third Edition, March 2016; most recently modified version published online December 2021).
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n.1964