Perilous, dangerous, precarious; desperate, hazardous, dire. (Now the usual sense.)

Ticklish; difficult to deal with, requiring great caution or skill; unsafe to meddle with; as to which one may easily go wrong or come to grief…

= ticklish, adj. 5. Now dialect.

That tends to tickle; difficult, critical, delicate, precarious, ticklish. Now dialect.

Of a matter or concern: uncertain, hazardous, tricky. Obsolete.

Liable to end in disaster unless treated with great care; needing cautious handling or action; delicate, critical, precarious, risky, hazardous.

Climacteric (in various senses); critical, decisive.

Involving risk of sudden fall or ruin; dangerous, precarious. Obsolete.

Difficult or tricky to deal with; requiring careful or cautious handling; precarious, risky; ticklish. Cf. sense 2b.

In extended use: constituting or having the effect of a critical event or point in time; critical, decisive; epochal.

Involving great uncertainty, danger, or risk; having the potential to produce a disastrous or extremely detrimental outcome.

Dependent on chance or circumstance; uncertain; liable to fail; exposed to risk, hazardous; insecure, unstable.

Uncertain as to the outcome; having the potential to result in failure or disaster; precarious, risky. Cf. sense A. 1b. In predicative use.

Risky, dangerous; uncertain, unreliable.