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单词 chlorothiazide
释义

chlorothiaziden.

/ˌklɔːrəʊˈθʌɪəzʌɪd//ˌklɒrəʊˈθʌɪəzʌɪd/
Etymology: < chloro- comb. form2 + thia(dia)z(ine + -ide suffix.
Chemistry.
A white crystalline powder, C7H6ClN3O4S2, used as a diuretic.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > cleansing or expelling medicines > [noun] > diuretic > specific
Haarlem oil1885
Salyrgan1924
mersalyl1936
acetazolamide1954
chlorothiazide1957
thiazide1959
triamterene1962
ethacrynic acid1963
frusemide1963
1957 Novello & Sprague in Jrnl. Amer. Chem. Soc. LXXIX. 2029/1 One compound of this type..has been selected for clinical trial and assigned the generic name of chlorothiazide.
1960 Jrnl. Org. Chem. 25 970/1 The generic name of chlorothiazide has been given to this compound and Diuril is the trademark of Merck and Co., Inc., for chlorothiazide.
1963 Brit. Pharmaceut. Codex 170 Chlorothiazide is a non-mercurial diuretic which reduces the resorption of electrolytes by the proximal renal tubes.
1963 Brit. Pharmaceut. Codex 170 Chlorothiazide is used for the treatment of œdema and of the toxæmias of pregnancy.
This entry has not yet been fully updated (first published 1972; most recently modified version published online March 2019).
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n.1957
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