1900*Alkylating agent [see main sense]. 1961 29 July 250/1 Chemotherapy with various alkylating agents.
1989 40 1016/1 Vacuum-distilled 4-vinylpyridine was used as the alkylating agent and the reaction was allowed to proceed overnight.
2003 Oct. 30/1 Temozolomide, a member of a class of anti-cancer drugs known as alkylating agents.