| 释义 |
cannabinoid, n. Chem.|ˈkænəbɪnɔɪd|
[f. cannabinol n. + -oid.]
Any of a group of closely related tricyclic compounds that includes cannabinol and cannabidiol.
1967Mechoulam & Gaoni in Fortschritte der Chemie Organischer Naturstoffe XXV. 178 We propose the term cannabinoids for the group of C21-compounds typical of and present in C. sativa, as well as for their analogs and transformation products. 1970Nature 20 June 1171/2 A placebo was composed from an extract of marijuana with cannabinoids removed. 1974M. C. Gerald Pharmacol. xviii. 339 Cannabis contains a group of closely related compounds that are collectively termed cannabinoids... These compounds do not contain a nitrogen atom and, therefore, are not alkaloids.
▸ cannabinoid receptor n. Physiol. any of a class of cellular receptors that bind exogenous cannabinoids and structurally related endogenous compounds such as anandamide, and which are found in the central nervous system and various other tissues.
1987Neuropharmacol. 26 507/1 The response to cannabinoids may be the result of stimulation of a ‘*cannabinoid’ receptor. 1988Molecular Pharmacol. 34 605 The determination and characterization of a cannabinoid receptor. 1990Sci. Amer. Oct. 15/3 The cannabinoid receptor is distinct from other types of drug receptors in the brain, such as those that bind to opiates. 1997New Scientist 5 July 4/1 Because cannabinoids linger in the brain for days, the team had to simulate rapid withdrawal by using a second drug to block the brain's cannabinoid receptors. |