| 释义 |
scrapie|ˈskreɪpɪ|
Also † scrapy.
[f. scrape v. + -ie, -y6.]
A subacute, invariably fatal, disease of sheep and goats, characterized by degeneration of the central nervous system, leading to uncoordinated gait and itching.
1910Vet. Jrnl. LXVI. 711 Shepherds and farmers..class more than one disease with totally different symptoms under the head of Scrapy. 1913Jrnl. Compar. Path. & Therapeut. XXVI. 317 The term ‘scrape’ or ‘scrapie’ is a popular one which has been applied to a disease of sheep on the borders of England and Scotland. 1914J. P. McGowan Investigation into Dis. of Sheep called ‘Scrapie’ i. 11 The disease has existed in Britain since before the middle of the eighteenth century under such names as ‘scrapie’, ‘scratchie’, ‘rubbers’, ‘rickets’, ‘goggles’, ‘shakings’, ‘shrew-croft’, and ‘cuddie-trot’. 1925Glasgow Herald 22 Apr. 7 Scrapie has mainly been confined to a certain area of the country. 1952I. E. Newsom Sheep Dis. iv. 120 Scrapie is a chronic neurosis of sheep and goats characterized by intense pruritus, progressive incoordination, weakness, paralysis and death. 1975Times 25 Aug. 8/5 Scrapie, an incurable disease of the nervous system, has afflicted various breeds of sheep for many years. 1979Nature 11 Jan. 127/1 Scrapie, a subacute neuromuscular disease of middle-aged sheep, has been attributed variously to an infection or to heredity. The clinical disorder follows progressive symmetrical decay of neurones in localised brain sites,..associated with a terminal axon dystrophy. 1981Brit. Vet. Jrnl. CXXXVII. 108/2 Although scrapie is caused by a virus-like agent, the development of clinical disease depends on genetic factors. |