| 释义 |
polynucleotide Biochem.|pɒlɪˈnjuːklɪətaɪd|
[ad. G. polynucleotid (Levene & Mandel 1908, in Ber. d. Deut. Chem. Ges. XLI. 1906): see poly- and nucleotide.]
A polymeric compound whose molecules are composed of a number (usu. large) of nucleotides.
1911Jrnl. Biol. Chem. IX. 394 Yeast nucleic acid is a polynucleotide. 1916[see hexose]. 1953S. E. Luria Gen. Virol. v. 100 Watson and Crick..have proposed for DNA a structure consisting of two helical polynucleotide chains coiled around the same axis and held together by bonds between the purine and pyrimidine bases. 1964G. H. Haggis et al. Introd. Molecular Biol. ix. 225 Nucleic acids formed by in vitro synthesis with restricted base composition are termed polynucleotides. Ibid. 226 Synthetic polynucleotides form a variety of double and triple helices. 1970R. W. McGilvery Biochem. iii. 23 A particular arrangement of three nucleotide units in the DNA polynucleotide specifies a particular amino acid. 1971Sci. Amer. July 28/2 Antibody responses in animals were enhanced by certain synthetic polynucleotides. These are analogues of the nucleic acids DNA or RNA that are made in the laboratory by combining nucleotides (the subunits of nucleic acids) in arbitrary ways. |