| 释义 |
nortriptyline, n. Pharm.|nɔːˈtrɪptɪliːn|
[f. nor- + tri- + heptyl n. + -ine5: cf. amitriptyline n., protriptyline n.]
A tricyclic antidepressant drug, C19H21N , given orally (frequently as the hydrochloride).
1962Jrnl. Nerv. & Mental Dis. CXXXIV. 564/1 Nortriptyline..is 5-(gamma-methylaminopropylidene) dibenzo[a,d]cyclohepta[1,4]diene hydrochloride. 1965J. Pollitt Depression & its Treatment iv. 57 The imipramine group of drugs includes imipramine (Tofranil), amitriptyline (Tryptizol, Saroten, Laroxyl), and nortriptyline (Allegron, Aventyl). 1978[see protriptyline n.]. 1986Approved Names (Brit. Pharmacopœia Comm.) 83 Nortriptyline, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-propyl(methyl)amine. 1988Chromatography CDXXXIX. 359 A chromatogram illustrating the separation of amitriptyline and nortriptyline, with complete recovery, from blood plasma is shown in Fig. 3. |