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单词 lepromin
释义 lepromin Med.|ˈlɛprəʊmɪn|
Also -ine.
[a. G. lepromin (P. Bargehr 1927, in Zeitschr. f. Immunitätsf. und exper. Ther. XLIX. 347): see leproma and -in1.]
A boiled saline extract of lepromatous tissue. So lepromin test, a test involving intradermal injection of lepromin and examination for a nodule at the site (see quot. 1951).
1932Monthly Bull. Philippine Health Service XII. 300 The leprolin (lepromin) used by Mitsuda, Bargehr, de Langen, de Vogel, Mariani, Muir and Hayashi were prepared in different ways.1940Rogers & Muir Leprosy (ed. 2) 248 The lepromin test is thus of use in measuring the natural resistance of the patient to leprous infection.1951Whitby & Hynes Med. Bacteriol. (ed. 5) xiv. 267 The lepromin test consists of the intradermal injection of a small quantity of the extract. The test is positive in milder types of leprosy and in many healthy contacts; it is negative in the more severe types of the disease which have a bad outlook.1959G. Greene Congo Jrnl. in In Search of a Character (1961) 89 Lepromine used to determine the resistance of an undetermined patient.1973Bryceson & Pfaltzgraff Leprosy for Students Med. vi. 62 Infection with M[ycobacterium] tuberculosis, immunization with BCG or previous skin testing with lepromin may, but does not necessarily, induce lepromin positivity in a normal person.
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