| 释义 |
labetalol, n. Pharm.|ləˈbiːtəlɒl|
[f. la- (perh. an inversion of alpha n.) + beta n. + *-olol.]
An α- and β-adrenoceptor blocking agent used in the treatment of hypertension, and occurring as four stereoisomers with different degrees of interaction; 2-hydroxy-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzamide, C19H24N2O3 .
1975Approved Names 1973 (Brit. Pharmacopœia Comm.) Suppl. v, Labetalol. 1977Lancet 23 Apr. 890/2 If the alpha-blocking potency of labetalol is sufficient to enhance blood-pressure control substantially, it may also be sufficient to cause disabling symptoms. 1985Brit. Med. Jrnl. 10 Aug. 366/1 In one study babies born to women taking labetalol were up to 500 g heavier than those from women taking atenolol. 1987Oxf. Textbk. Med. (ed. 2) II. xiii. 374/2 Although the α-blocking potency is relatively mild labetalol appears to be significantly better in hypotensive potency than a β-blocker alone. |